Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran
Introduction. Non-motor symptoms (NMS) are common in Parkinson’s disease. It can be predominant as the disease advances, thereby constituting a major source of disease burden for patients. Current study was conducted to determine the prevalence of these symptoms in the north of Iran. Method. This c...
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2019-12-01
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| Series: | Romanian Journal of Neurology |
| Subjects: | |
| Online Access: | https://rjn.com.ro/articles/2019.4/RJN_2019_4_Art-05.pdf |
| _version_ | 1811204709108678656 |
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| author | Seyed Mohammad Masood Hojjati Arman Farrasat Hoda Naghshineh Ali Alizadeh-Khatir Alijan Ahmadi Ahangar Payam Saadat Shayan Alijanpour |
| author_facet | Seyed Mohammad Masood Hojjati Arman Farrasat Hoda Naghshineh Ali Alizadeh-Khatir Alijan Ahmadi Ahangar Payam Saadat Shayan Alijanpour |
| author_sort | Seyed Mohammad Masood Hojjati |
| collection | DOAJ |
| description | Introduction. Non-motor symptoms (NMS) are common in Parkinson’s disease. It can be predominant as the disease advances, thereby constituting a major source of disease burden for patients. Current study was conducted to determine the prevalence of these symptoms in the north of Iran.
Method. This cross-sectional study was performed on 109 patients with Parkinson’s disease in Ayatollah Rouhani Hospital in Babol, North of Iran, during 2017-2018. NMS were obtained from a NMS standard questionnaire containing 30 questions plus the clinical and demographic information in a separate checklist of patients. NMS were then classified into nine distinct categories. The association of NMS with clinical and demographic variables was evaluated by the SPSS software version 23. In all cases, the significance level of the tests was less than 0.05.
Results. The mean age of the patients was 70.59 ± 9.69 years (46-97 years) and 61 (56%) were male. The duration of the disease was 5.61 ± 4.89 years. NMS associated with sleep / fatigue with the prevalence of 76.1% were the most prevalent symptoms. NMS related to mood / cognition with frequency of 65.1%, cardiovascular with 51.4% and miscellaneous with 51.4% frequency were the most commonly reported symptoms in patients. Severity of the disease was significantly correlated with the symptoms of the cardiovascular, attention / memory and GI tract (P = 0.001). Age and education of the patients with cardiovascular symptoms and attention / memory had a significant relationship (P < 0.05). Occupation and marriage of the patients were significant with attention/memory symptoms (P < 0.05).
Conclusions. The sleep-related symptoms and fatigue were the most common NMSs in Parkinson’s patients. Also, the severity of the disease and ageing were statistically significant with the prevalence of the NMS in patients. Therefore, consideration should be given to older patients suffering from more severe Parkinson’s disease. |
| first_indexed | 2024-04-12T03:18:18Z |
| format | Article |
| id | doaj.art-28436166b1034fc194a319587561098c |
| institution | Directory Open Access Journal |
| issn | 1843-8148 2069-6094 |
| language | English |
| last_indexed | 2024-04-12T03:18:18Z |
| publishDate | 2019-12-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Neurology |
| spelling | doaj.art-28436166b1034fc194a319587561098c2022-12-22T03:49:59ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942019-12-0118418419010.37897/RJN.2019.4.5Non-motor symptoms in patients with Parkinson’s disease in Babol, North of IranSeyed Mohammad Masood Hojjati0Arman Farrasat1Hoda Naghshineh2Ali Alizadeh-Khatir3Alijan Ahmadi Ahangar4Payam Saadat5Shayan Alijanpour6Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran; Clinical Research Development Unite of Rouhani Hospital, Babol University of Medical Sciences, Babol, I.R. IranStudent Research Committee, Babol University of Medical Sciences, Babol, I.R. IranMobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. IranMobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran; Clinical Research Development Unite of Rouhani Hospital, Babol University of Medical Sciences, Babol, I.R. IranStudent Research Committee, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, I.R. IranIntroduction. Non-motor symptoms (NMS) are common in Parkinson’s disease. It can be predominant as the disease advances, thereby constituting a major source of disease burden for patients. Current study was conducted to determine the prevalence of these symptoms in the north of Iran. Method. This cross-sectional study was performed on 109 patients with Parkinson’s disease in Ayatollah Rouhani Hospital in Babol, North of Iran, during 2017-2018. NMS were obtained from a NMS standard questionnaire containing 30 questions plus the clinical and demographic information in a separate checklist of patients. NMS were then classified into nine distinct categories. The association of NMS with clinical and demographic variables was evaluated by the SPSS software version 23. In all cases, the significance level of the tests was less than 0.05. Results. The mean age of the patients was 70.59 ± 9.69 years (46-97 years) and 61 (56%) were male. The duration of the disease was 5.61 ± 4.89 years. NMS associated with sleep / fatigue with the prevalence of 76.1% were the most prevalent symptoms. NMS related to mood / cognition with frequency of 65.1%, cardiovascular with 51.4% and miscellaneous with 51.4% frequency were the most commonly reported symptoms in patients. Severity of the disease was significantly correlated with the symptoms of the cardiovascular, attention / memory and GI tract (P = 0.001). Age and education of the patients with cardiovascular symptoms and attention / memory had a significant relationship (P < 0.05). Occupation and marriage of the patients were significant with attention/memory symptoms (P < 0.05). Conclusions. The sleep-related symptoms and fatigue were the most common NMSs in Parkinson’s patients. Also, the severity of the disease and ageing were statistically significant with the prevalence of the NMS in patients. Therefore, consideration should be given to older patients suffering from more severe Parkinson’s disease.https://rjn.com.ro/articles/2019.4/RJN_2019_4_Art-05.pdfparkinson’s diseasenon-motor symptomsseverity of diseaseduration of diseasepriority sign |
| spellingShingle | Seyed Mohammad Masood Hojjati Arman Farrasat Hoda Naghshineh Ali Alizadeh-Khatir Alijan Ahmadi Ahangar Payam Saadat Shayan Alijanpour Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran Romanian Journal of Neurology parkinson’s disease non-motor symptoms severity of disease duration of disease priority sign |
| title | Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran |
| title_full | Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran |
| title_fullStr | Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran |
| title_full_unstemmed | Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran |
| title_short | Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran |
| title_sort | non motor symptoms in patients with parkinson s disease in babol north of iran |
| topic | parkinson’s disease non-motor symptoms severity of disease duration of disease priority sign |
| url | https://rjn.com.ro/articles/2019.4/RJN_2019_4_Art-05.pdf |
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