Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy
Abstract Background With the more advanced science in the field of medicine and disease management, the population of geriatric intensive care patients is increasing. The COVID-19 pandemic has impacted healthcare management around the globe, especially on critically-ill elderly patients. We aim to a...
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-06-01
|
| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-022-03227-9 |
| _version_ | 1818545940259143680 |
|---|---|
| author | Nancy Margarita Rehatta Susilo Chandra Djayanti Sari Mayang Indah Lestari Tjokorda Gde Agung Senapathi Haizah Nurdin Belindo Wirabuana Bintang Pramodana Adinda Putra Pradhana Isngadi Isngadi Novita Anggraeni Kenanga Marwan Sikumbang Radian Ahmad Halimi Zafrullah Khany Jasa Akhyar Hamonangan Nasution Mochamat Mochamat Purwoko Purwoko |
| author_facet | Nancy Margarita Rehatta Susilo Chandra Djayanti Sari Mayang Indah Lestari Tjokorda Gde Agung Senapathi Haizah Nurdin Belindo Wirabuana Bintang Pramodana Adinda Putra Pradhana Isngadi Isngadi Novita Anggraeni Kenanga Marwan Sikumbang Radian Ahmad Halimi Zafrullah Khany Jasa Akhyar Hamonangan Nasution Mochamat Mochamat Purwoko Purwoko |
| author_sort | Nancy Margarita Rehatta |
| collection | DOAJ |
| description | Abstract Background With the more advanced science in the field of medicine and disease management, the population of geriatric intensive care patients is increasing. The COVID-19 pandemic has impacted healthcare management around the globe, especially on critically-ill elderly patients. We aim to analyse the relationship between underlying illnesses, including COVID-19, and the survival rate of elderly patients who are treated in the intensive care setting. Methods We conducted a prospective cohort study at 14 teaching hospitals for Anaesthesiology and Intensive Therapy Education in Indonesia. We selected all subjects with 60 years of age or older in the period between February to May 2021. Variables recorded included subject characteristics, comorbidities, and COVID-19 status. Subjects were followed for 30-day mortality as an outcome. We analysed the data using Kaplan-Meier survival analysis. Results We recruited 982 elderly patients, and 728 subjects were in the final analysis (60.7% male; 68.0 ± 6.6 years old). The 30-day mortality was 38.6%. The top five comorbidities are hypertension (21.1%), diabetes (16.2%), moderate or severe renal disease (10.6%), congestive heart failure (9.2%), and cerebrovascular disease (9.1%). Subjects with Charlson’s Comorbidity Index Score > 5 experienced 66% death. Subjects with COVID-19 who died were 57.4%. Subjects with comorbidities and COVID-19 had lower survival time than subjects without those conditions (p < 0.005). Based on linear correlation analysis, the more comorbidities the geriatric patients in the ICU had, the higher chance of mortality in 30 days (p < 0.005, R coefficient 0.22). Conclusion Approximately one in four elderly intensive care patients die, and the number is increasing with comorbidities and COVID-19 status. |
| first_indexed | 2024-12-12T07:46:32Z |
| format | Article |
| id | doaj.art-284526f54e904663a77e9c57e687e012 |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-12-12T07:46:32Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-284526f54e904663a77e9c57e687e0122022-12-22T00:32:35ZengBMCBMC Geriatrics1471-23182022-06-012211910.1186/s12877-022-03227-9Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive TherapyNancy Margarita Rehatta0Susilo Chandra1Djayanti Sari2Mayang Indah Lestari3Tjokorda Gde Agung Senapathi4Haizah Nurdin5Belindo Wirabuana6Bintang Pramodana7Adinda Putra Pradhana8Isngadi Isngadi9Novita Anggraeni10Kenanga Marwan Sikumbang11Radian Ahmad Halimi12Zafrullah Khany Jasa13Akhyar Hamonangan Nasution14Mochamat Mochamat15Purwoko Purwoko16Department of Anaesthesiology and Reanimation, Faculty of Medicine, Universitas AirlanggaDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas IndonesiaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah MadaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine Universitas SriwijayaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas UdayanaDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas HasanuddinDepartment of Anaesthesiology and Reanimation, Faculty of Medicine, Universitas AirlanggaDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas IndonesiaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas UdayanaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas BrawijayaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas RiauDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Lambung MangkuratDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas PadjadjaranDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Syiah KualaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera UtaraDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas DiponegoroDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sebelas MaretAbstract Background With the more advanced science in the field of medicine and disease management, the population of geriatric intensive care patients is increasing. The COVID-19 pandemic has impacted healthcare management around the globe, especially on critically-ill elderly patients. We aim to analyse the relationship between underlying illnesses, including COVID-19, and the survival rate of elderly patients who are treated in the intensive care setting. Methods We conducted a prospective cohort study at 14 teaching hospitals for Anaesthesiology and Intensive Therapy Education in Indonesia. We selected all subjects with 60 years of age or older in the period between February to May 2021. Variables recorded included subject characteristics, comorbidities, and COVID-19 status. Subjects were followed for 30-day mortality as an outcome. We analysed the data using Kaplan-Meier survival analysis. Results We recruited 982 elderly patients, and 728 subjects were in the final analysis (60.7% male; 68.0 ± 6.6 years old). The 30-day mortality was 38.6%. The top five comorbidities are hypertension (21.1%), diabetes (16.2%), moderate or severe renal disease (10.6%), congestive heart failure (9.2%), and cerebrovascular disease (9.1%). Subjects with Charlson’s Comorbidity Index Score > 5 experienced 66% death. Subjects with COVID-19 who died were 57.4%. Subjects with comorbidities and COVID-19 had lower survival time than subjects without those conditions (p < 0.005). Based on linear correlation analysis, the more comorbidities the geriatric patients in the ICU had, the higher chance of mortality in 30 days (p < 0.005, R coefficient 0.22). Conclusion Approximately one in four elderly intensive care patients die, and the number is increasing with comorbidities and COVID-19 status.https://doi.org/10.1186/s12877-022-03227-9Intensive careGeriatricCharacteristicsOutcome |
| spellingShingle | Nancy Margarita Rehatta Susilo Chandra Djayanti Sari Mayang Indah Lestari Tjokorda Gde Agung Senapathi Haizah Nurdin Belindo Wirabuana Bintang Pramodana Adinda Putra Pradhana Isngadi Isngadi Novita Anggraeni Kenanga Marwan Sikumbang Radian Ahmad Halimi Zafrullah Khany Jasa Akhyar Hamonangan Nasution Mochamat Mochamat Purwoko Purwoko Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy BMC Geriatrics Intensive care Geriatric Characteristics Outcome |
| title | Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy |
| title_full | Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy |
| title_fullStr | Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy |
| title_full_unstemmed | Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy |
| title_short | Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy |
| title_sort | comorbidities and covid 19 status influence the survival rate of geriatric patients in intensive care units a prospective cohort study from the indonesian society of anaesthesiology and intensive therapy |
| topic | Intensive care Geriatric Characteristics Outcome |
| url | https://doi.org/10.1186/s12877-022-03227-9 |
| work_keys_str_mv | AT nancymargaritarehatta comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT susilochandra comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT djayantisari comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT mayangindahlestari comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT tjokordagdeagungsenapathi comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT haizahnurdin comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT belindowirabuana comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT bintangpramodana comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT adindaputrapradhana comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT isngadiisngadi comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT novitaanggraeni comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT kenangamarwansikumbang comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT radianahmadhalimi comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT zafrullahkhanyjasa comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT akhyarhamonangannasution comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT mochamatmochamat comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy AT purwokopurwoko comorbiditiesandcovid19statusinfluencethesurvivalrateofgeriatricpatientsinintensivecareunitsaprospectivecohortstudyfromtheindonesiansocietyofanaesthesiologyandintensivetherapy |