Classification and Antigen Molecules of Autoimmune Bullous Diseases
Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/13/4/703 |
| _version_ | 1797606196910227456 |
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| author | Takashi Hashimoto Hua Qian Norito Ishii Takekuni Nakama Chiharu Tateishi Daisuke Tsuruta Xiaoguang Li |
| author_facet | Takashi Hashimoto Hua Qian Norito Ishii Takekuni Nakama Chiharu Tateishi Daisuke Tsuruta Xiaoguang Li |
| author_sort | Takashi Hashimoto |
| collection | DOAJ |
| description | Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs have been classified into a number of distinct subtypes by clinical and histopathological findings, and immunological characteristics. In addition, various biochemical and molecular biological studies have identified various novel autoantigens in AIBDs, which has resulted in proposals of new subtypes of AIBDs. In this article, we summarized various distinct AIBDs, and proposed the latest and most comprehensive classification of AIBDs with their autoantigen molecules. |
| first_indexed | 2024-03-11T05:11:47Z |
| format | Article |
| id | doaj.art-284cb507be7d4091ba0a2826f72b68c3 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-11T05:11:47Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-284cb507be7d4091ba0a2826f72b68c32023-11-17T18:30:09ZengMDPI AGBiomolecules2218-273X2023-04-0113470310.3390/biom13040703Classification and Antigen Molecules of Autoimmune Bullous DiseasesTakashi Hashimoto0Hua Qian1Norito Ishii2Takekuni Nakama3Chiharu Tateishi4Daisuke Tsuruta5Xiaoguang Li6Department of Dermatology, Osaka Metropolitan University Graduate School of Medicine, Osaka 545-8585, JapanDepartment of Laboratory Medicine, Medical College, Dalian University, Dalian 116622, ChinaDepartment of Dermatology, Kurume University School of Medicine, Kurume 830-0011, JapanDepartment of Dermatology, Kurume University School of Medicine, Kurume 830-0011, JapanDepartment of Dermatology, Osaka Metropolitan University Graduate School of Medicine, Osaka 545-8585, JapanDepartment of Dermatology, Osaka Metropolitan University Graduate School of Medicine, Osaka 545-8585, JapanDepartment of Laboratory Medicine, Medical College, Dalian University, Dalian 116622, ChinaAutoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs have been classified into a number of distinct subtypes by clinical and histopathological findings, and immunological characteristics. In addition, various biochemical and molecular biological studies have identified various novel autoantigens in AIBDs, which has resulted in proposals of new subtypes of AIBDs. In this article, we summarized various distinct AIBDs, and proposed the latest and most comprehensive classification of AIBDs with their autoantigen molecules.https://www.mdpi.com/2218-273X/13/4/703autoimmune bullous diseasesautoantibodyclassificationautoantigen moleculessubtypespemphigus |
| spellingShingle | Takashi Hashimoto Hua Qian Norito Ishii Takekuni Nakama Chiharu Tateishi Daisuke Tsuruta Xiaoguang Li Classification and Antigen Molecules of Autoimmune Bullous Diseases Biomolecules autoimmune bullous diseases autoantibody classification autoantigen molecules subtypes pemphigus |
| title | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
| title_full | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
| title_fullStr | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
| title_full_unstemmed | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
| title_short | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
| title_sort | classification and antigen molecules of autoimmune bullous diseases |
| topic | autoimmune bullous diseases autoantibody classification autoantigen molecules subtypes pemphigus |
| url | https://www.mdpi.com/2218-273X/13/4/703 |
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