In silico and in vitro screening of pyrrole-based Hydrazide-Hydrazones as novel acetylcholinesterase inhibitors
Virtual screening is emerging as a highly applied technique and gained prominence as widely used method for the search and identification of potential hits, significantly reducing the time needed to discover novel and effective compounds compared to high-throughput screening. Recently, the superiori...
Main Authors: | Emilio Mateev, Ali Irfan, Alexandrina Mateeva, Magdalena Kondeva-Burdina, Maya Georgieva, Alexander Zlatkov |
---|---|
Format: | Article |
Language: | English |
Published: |
Pensoft Publishers
2024-02-01
|
Series: | Pharmacia |
Online Access: | https://pharmacia.pensoft.net/article/114120/download/pdf/ |
Similar Items
-
In Silico and Chromatographic Methods for Analysis of Biotransformation of Prospective Neuroprotective Pyrrole-Based Hydrazone in Isolated Rat Hepatocytes
by: Alexandrina Mateeva, et al.
Published: (2024-03-01) -
Optimization and validation of RP-HPLC method for evaluation of pyrrole -containing hydrazones in isolated rat synaptosomes
by: Alexandrina Mateeva, et al.
Published: (2023-10-01) -
Design, microwave-assisted synthesis, biological evaluation, molecular docking and ADME studies of pyrrole-based hydrazide-hydrazones as potential antioxidant agents
by: Emilio Mateev, et al.
Published: (2022-12-01) -
In Silico Evaluation and In Vitro Determination of Neuroprotective and MAO-B Inhibitory Effects of Pyrrole-Based Hydrazones: A Therapeutic Approach to Parkinson’s Disease
by: Magdalena Kondeva-Burdina, et al.
Published: (2022-12-01) -
Microwave-assisted organic synthesis of pyrroles (Review)
by: Emilio Mateev, et al.
Published: (2024-03-01)