Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis
Chronic autoimmune thyroiditis (CAT) is the most common thyroid disorder in the pediatric population. Ultrasound evaluation may suggest the diagnosis. Additionally, shear-wave elastography (SWE) proved to be a valuable additional diagnosis tool in adults with CAT by assessing thyroid stiffness (TS)....
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MDPI AG
2021-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/2/248 |
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| author | Cristina Mihaela Cepeha Corina Paul Andreea Borlea Renata Fofiu Florin Borcan Cristina Adriana Dehelean Viviana Ivan Dana Stoian |
| author_facet | Cristina Mihaela Cepeha Corina Paul Andreea Borlea Renata Fofiu Florin Borcan Cristina Adriana Dehelean Viviana Ivan Dana Stoian |
| author_sort | Cristina Mihaela Cepeha |
| collection | DOAJ |
| description | Chronic autoimmune thyroiditis (CAT) is the most common thyroid disorder in the pediatric population. Ultrasound evaluation may suggest the diagnosis. Additionally, shear-wave elastography (SWE) proved to be a valuable additional diagnosis tool in adults with CAT by assessing thyroid stiffness (TS). This study aims to assess its use also in detecting children with CAT. The study group consisted of 50 children with confirmed diagnosis of CAT, who were compared to the control group, consisting of 50 children with no thyroid pathology and with an adult group of 50 subjects with CAT. The evaluation included, besides bioimmunochemical evaluation, also thyroid ultrasound evaluation and elastography measurements in the same session (Aixplorer Mach 30, Supersonic imagine, France). The mean TS values were significantly lower for children in the CAT group compared to adults with CAT (15.51 ± 4.76 kPa vs. 20.96 ± 6.31 kPa; <i>p</i> < 0.0001) and higher compared to the healthy aged matched controls (15.51 ± 4.76 kPa vs. 10.41 ± 2.01 kPa; <i>p</i> < 0.0001). SWE elastography definitely seems a promising technique in the evaluation of children with autoimmune thyroid pathology. |
| first_indexed | 2024-03-09T05:30:01Z |
| format | Article |
| id | doaj.art-285018a5628446f189eee992c08c24ac |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T05:30:01Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-285018a5628446f189eee992c08c24ac2023-12-03T12:32:49ZengMDPI AGDiagnostics2075-44182021-02-0111224810.3390/diagnostics11020248Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune ThyroiditisCristina Mihaela Cepeha0Corina Paul1Andreea Borlea2Renata Fofiu3Florin Borcan4Cristina Adriana Dehelean5Viviana Ivan6Dana Stoian7PhD School Department, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaDepartment of Pediatrics, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaPhD School Department, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaPhD School Department, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Pharmacy, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Pharmacy, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaDepartment of Internal Medicine II, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaDepartment of Internal Medicine II, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, RomaniaChronic autoimmune thyroiditis (CAT) is the most common thyroid disorder in the pediatric population. Ultrasound evaluation may suggest the diagnosis. Additionally, shear-wave elastography (SWE) proved to be a valuable additional diagnosis tool in adults with CAT by assessing thyroid stiffness (TS). This study aims to assess its use also in detecting children with CAT. The study group consisted of 50 children with confirmed diagnosis of CAT, who were compared to the control group, consisting of 50 children with no thyroid pathology and with an adult group of 50 subjects with CAT. The evaluation included, besides bioimmunochemical evaluation, also thyroid ultrasound evaluation and elastography measurements in the same session (Aixplorer Mach 30, Supersonic imagine, France). The mean TS values were significantly lower for children in the CAT group compared to adults with CAT (15.51 ± 4.76 kPa vs. 20.96 ± 6.31 kPa; <i>p</i> < 0.0001) and higher compared to the healthy aged matched controls (15.51 ± 4.76 kPa vs. 10.41 ± 2.01 kPa; <i>p</i> < 0.0001). SWE elastography definitely seems a promising technique in the evaluation of children with autoimmune thyroid pathology.https://www.mdpi.com/2075-4418/11/2/248elastographythyroiditisthyroid stiffness |
| spellingShingle | Cristina Mihaela Cepeha Corina Paul Andreea Borlea Renata Fofiu Florin Borcan Cristina Adriana Dehelean Viviana Ivan Dana Stoian Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis Diagnostics elastography thyroiditis thyroid stiffness |
| title | Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis |
| title_full | Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis |
| title_fullStr | Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis |
| title_full_unstemmed | Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis |
| title_short | Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis |
| title_sort | shear wave elastography diagnostic value in children with chronic autoimmune thyroiditis |
| topic | elastography thyroiditis thyroid stiffness |
| url | https://www.mdpi.com/2075-4418/11/2/248 |
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