Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-Plasticiser
The melting behaviour of the triblock polymers, Pluronic F38, F68, F77, F108, and F127, was investigated in pressurised CO<sub>2</sub> and in the presence of menthol. The melting points of the polymers combined with 0, 10, 25, and 50 wt% of menthol were studied at atmospheric pressure an...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/14/2825 |
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| author | Vivek Trivedi Adejumoke Lara Ajiboye Nichola J. Coleman Ruchir Bhomia Marion Bascougnano |
| author_facet | Vivek Trivedi Adejumoke Lara Ajiboye Nichola J. Coleman Ruchir Bhomia Marion Bascougnano |
| author_sort | Vivek Trivedi |
| collection | DOAJ |
| description | The melting behaviour of the triblock polymers, Pluronic F38, F68, F77, F108, and F127, was investigated in pressurised CO<sub>2</sub> and in the presence of menthol. The melting points of the polymers combined with 0, 10, 25, and 50 wt% of menthol were studied at atmospheric pressure and compared with those at 10 and 20 MPa in supercritical carbon dioxide (scCO<sub>2</sub>). The highest melting point depressions of 16.8 ± 0.5 °C and 29.0 ± 0.3 °C were observed at 10 and 20 MPa, respectively. The melting point of triblock polymers in pressurised CO<sub>2</sub> was found to be dependent on molecular weight, poly(propylene oxide) (PPO) content, and menthol percentage. The melting point of most of the polymers studied in this work can be reduced to room temperature, which can be pivotal to the formulation development of thermolabile substances using these polymers. |
| first_indexed | 2024-03-09T13:08:23Z |
| format | Article |
| id | doaj.art-285651120c0e455a9d2357dbb8b0329d |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T13:08:23Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-285651120c0e455a9d2357dbb8b0329d2023-11-30T21:44:36ZengMDPI AGPolymers2073-43602022-07-011414282510.3390/polym14142825Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-PlasticiserVivek Trivedi0Adejumoke Lara Ajiboye1Nichola J. Coleman2Ruchir Bhomia3Marion Bascougnano4Medway School of Pharmacy, University of Kent, Central Avenue, Chatham Maritime, Kent ME4 4TB, UKMedway School of Pharmacy, University of Kent, Central Avenue, Chatham Maritime, Kent ME4 4TB, UKDepartment of Pharmaceutical, Chemical and Environmental Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, UKProcter & Gamble, 452 Basingstoke Road, Reading RG2 0RX, UKDepartment of Pharmaceutical, Chemical and Environmental Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, UKThe melting behaviour of the triblock polymers, Pluronic F38, F68, F77, F108, and F127, was investigated in pressurised CO<sub>2</sub> and in the presence of menthol. The melting points of the polymers combined with 0, 10, 25, and 50 wt% of menthol were studied at atmospheric pressure and compared with those at 10 and 20 MPa in supercritical carbon dioxide (scCO<sub>2</sub>). The highest melting point depressions of 16.8 ± 0.5 °C and 29.0 ± 0.3 °C were observed at 10 and 20 MPa, respectively. The melting point of triblock polymers in pressurised CO<sub>2</sub> was found to be dependent on molecular weight, poly(propylene oxide) (PPO) content, and menthol percentage. The melting point of most of the polymers studied in this work can be reduced to room temperature, which can be pivotal to the formulation development of thermolabile substances using these polymers.https://www.mdpi.com/2073-4360/14/14/2825melting point depressiontriblock polymerssupercritical carbon dioxidesolid co-plasticiser |
| spellingShingle | Vivek Trivedi Adejumoke Lara Ajiboye Nichola J. Coleman Ruchir Bhomia Marion Bascougnano Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-Plasticiser Polymers melting point depression triblock polymers supercritical carbon dioxide solid co-plasticiser |
| title | Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-Plasticiser |
| title_full | Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-Plasticiser |
| title_fullStr | Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-Plasticiser |
| title_full_unstemmed | Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-Plasticiser |
| title_short | Melting Point Depression of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Polymers in Supercritical Carbon Dioxide in the Presence of Menthol as a Solid Co-Plasticiser |
| title_sort | melting point depression of poly ethylene oxide poly propylene oxide poly ethylene oxide triblock polymers in supercritical carbon dioxide in the presence of menthol as a solid co plasticiser |
| topic | melting point depression triblock polymers supercritical carbon dioxide solid co-plasticiser |
| url | https://www.mdpi.com/2073-4360/14/14/2825 |
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