Establishment of a Novel Detection Platform for Clostridioides difficile Toxin Genes Based on Orthogonal CRISPR

Establishment of a Novel Detection Platform for Clostridioides difficile Toxin Genes Based on Orthogonal CRISPR

ABSTRACT Clostridioides difficile is one of the leading pathogens causing nosocomial infection. The infection can range from mild to severe, and rapid identification is pivotal for early clinical diagnosis and appropriate treatment. Here, a genetic testing platform for toxins, referred to as OC-MAB...

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Bibliographic Details
Main Authors: Tong Jiang, Xinyi Hu, Jilu Shen
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Clostridioides difficile
orthogonal CRISPR system
immunochromatographic test strips
multiple RPA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01886-23

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