The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19
ABSTRACTThis study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-01-01
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| Series: | Emerging Microbes and Infections |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2020.1744483 |
| _version_ | 1797265854384046080 |
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| author | Liang Su Xiang Ma Huafeng Yu Zhaohua Zhang Pengfei Bian Yuling Han Jing Sun Yanqin Liu Chun Yang Jin Geng Zhongfa Zhang Zhongtao Gai |
| author_facet | Liang Su Xiang Ma Huafeng Yu Zhaohua Zhang Pengfei Bian Yuling Han Jing Sun Yanqin Liu Chun Yang Jin Geng Zhongfa Zhang Zhongtao Gai |
| author_sort | Liang Su |
| collection | DOAJ |
| description | ABSTRACTThis study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and imaging characteristics. All the children were detected positive result after their families onset. Three children had fever (22.2%) or cough (11.2%) symptoms and six (66.7%) children had no symptom. Among the 14 adult patients, the major symptoms included fever (57.1%), cough (35.7%), chest tightness/pain (21.4%), fatigue (21.4%) and sore throat (7.1%). Nearly 70% of the patients had normal (71.4%) or decreased (28.6%) white blood cell counts, and 50% (7/14) had lymphocytopenia. There were 10 adults (71.4%) showed abnormal imaging. The main manifestations were pulmonary consolidation (70%), nodular shadow (50%), and ground glass opacity (50%). Five discharged children were admitted again because their stool showed positive result in SARS-CoV-2 PCR. COVID-19 in children is mainly caused by family transmission, and their symptoms are mild and prognosis is better than adult. However, their PCR result in stool showed longer time than their families. Because of the mild or asymptomatic clinical process, it is difficult to recognize early for pediatrician and public health staff. |
| first_indexed | 2024-03-07T17:23:47Z |
| format | Article |
| id | doaj.art-285a6e4cdc9947da963654fc088f76aa |
| institution | Directory Open Access Journal |
| issn | 2222-1751 |
| language | English |
| last_indexed | 2024-04-25T00:51:25Z |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj.art-285a6e4cdc9947da963654fc088f76aa2024-03-11T16:04:24ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512020-01-019170771310.1080/22221751.2020.1744483The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19Liang Su0Xiang Ma1Huafeng Yu2Zhaohua Zhang3Pengfei Bian4Yuling Han5Jing Sun6Yanqin Liu7Chun Yang8Jin Geng9Zhongfa Zhang10Zhongtao Gai11Department of infectious diseases, Jinan Infectious diseases Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of infectious diseases, Jinan Infectious diseases Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of infectious diseases, Jinan Infectious diseases Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of infectious diseases, Jinan Infectious diseases Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of infectious diseases, Jinan Infectious diseases Hospital of Shandong University, Jinan, People’s Republic of ChinaDepartment of Respiratory, Qilu Children’s Hospital of Shandong University, Jinan, People’s Republic of ChinaABSTRACTThis study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and imaging characteristics. All the children were detected positive result after their families onset. Three children had fever (22.2%) or cough (11.2%) symptoms and six (66.7%) children had no symptom. Among the 14 adult patients, the major symptoms included fever (57.1%), cough (35.7%), chest tightness/pain (21.4%), fatigue (21.4%) and sore throat (7.1%). Nearly 70% of the patients had normal (71.4%) or decreased (28.6%) white blood cell counts, and 50% (7/14) had lymphocytopenia. There were 10 adults (71.4%) showed abnormal imaging. The main manifestations were pulmonary consolidation (70%), nodular shadow (50%), and ground glass opacity (50%). Five discharged children were admitted again because their stool showed positive result in SARS-CoV-2 PCR. COVID-19 in children is mainly caused by family transmission, and their symptoms are mild and prognosis is better than adult. However, their PCR result in stool showed longer time than their families. Because of the mild or asymptomatic clinical process, it is difficult to recognize early for pediatrician and public health staff.https://www.tandfonline.com/doi/10.1080/22221751.2020.1744483Coronavirussevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)clinical characteristicscorona virus diseases-19 (COVID-19)children |
| spellingShingle | Liang Su Xiang Ma Huafeng Yu Zhaohua Zhang Pengfei Bian Yuling Han Jing Sun Yanqin Liu Chun Yang Jin Geng Zhongfa Zhang Zhongtao Gai The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19 Emerging Microbes and Infections Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clinical characteristics corona virus diseases-19 (COVID-19) children |
| title | The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19 |
| title_full | The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19 |
| title_fullStr | The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19 |
| title_full_unstemmed | The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19 |
| title_short | The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19 |
| title_sort | different clinical characteristics of corona virus disease cases between children and their families in china the character of children with covid 19 |
| topic | Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clinical characteristics corona virus diseases-19 (COVID-19) children |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2020.1744483 |
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