Extracellularly Released Calreticulin Induced by Endoplasmic Reticulum Stress Impairs Syncytialization of Cytotrophoblast Model BeWo Cells

Extracellularly Released Calreticulin Induced by Endoplasmic Reticulum Stress Impairs Syncytialization of Cytotrophoblast Model BeWo Cells

The pregnancy-specific syndrome preeclampsia is a major cause of maternal mortality throughout the world. The initial insult resulting in the development of preeclampsia is inadequate trophoblast invasion, which may lead to reduced maternal perfusion of the placenta and placental dysfunction, such a...

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Bibliographic Details
Main Authors: Naoyuki Iwahashi, Midori Ikezaki, Kazuchika Nishitsuji, Madoka Yamamoto, Ibu Matsuzaki, Naoki Kato, Naoyuki Takaoka, Mana Taniguchi, Shin-ichi Murata, Kazuhiko Ino, Yoshito Ihara
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
calreticulin
syncytialization
trophoblast
preeclampsia
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/2073-4409/10/6/1305

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