Specific features of gastroesophageal reflux disease associated with obesity and overweight
Aim. To reveal the specific features of gastroesophageal reflux disease (GERD) associated with obesity and overweight, by investigating the clinical and endoscopic manifestations of the disease, 24-hour pH-metry scores, and leptin levels. Subjects and methods. A total of 131 patients with GERD were...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2016-02-01
|
| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/31908/pdf |
| _version_ | 1818129506116829184 |
|---|---|
| author | M A Livzan I V Lapteva T S Krolevets I E Kiselev |
| author_facet | M A Livzan I V Lapteva T S Krolevets I E Kiselev |
| author_sort | M A Livzan |
| collection | DOAJ |
| description | Aim. To reveal the specific features of gastroesophageal reflux disease (GERD) associated with obesity and overweight, by investigating the clinical and endoscopic manifestations of the disease, 24-hour pH-metry scores, and leptin levels. Subjects and methods. A total of 131 patients with GERD were examined. The data about complaints and those from life and medical histories were collected; anthropometric measurements and the results of blood biochemical tests, esophagoduodenoscopy (EPDS), and pH-metry were assessed; and the serum levels of leptin and its receptor were estimated. The patients were allocated into a study group (104 obese and/or overweight patients) and a comparison one (27 normal weight people). Results. Waist circumference, hip circumference, and blood glucose levels proved to be statistically significantly higher in the study group (p |
| first_indexed | 2024-12-11T07:50:13Z |
| format | Article |
| id | doaj.art-2861bf78de8a412f9e6a176027bf64b0 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-11T07:50:13Z |
| publishDate | 2016-02-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-2861bf78de8a412f9e6a176027bf64b02022-12-22T01:15:22Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422016-02-01882212728924Specific features of gastroesophageal reflux disease associated with obesity and overweightM A LivzanI V LaptevaT S KrolevetsI E KiselevAim. To reveal the specific features of gastroesophageal reflux disease (GERD) associated with obesity and overweight, by investigating the clinical and endoscopic manifestations of the disease, 24-hour pH-metry scores, and leptin levels. Subjects and methods. A total of 131 patients with GERD were examined. The data about complaints and those from life and medical histories were collected; anthropometric measurements and the results of blood biochemical tests, esophagoduodenoscopy (EPDS), and pH-metry were assessed; and the serum levels of leptin and its receptor were estimated. The patients were allocated into a study group (104 obese and/or overweight patients) and a comparison one (27 normal weight people). Results. Waist circumference, hip circumference, and blood glucose levels proved to be statistically significantly higher in the study group (phttps://ter-arkhiv.ru/0040-3660/article/viewFile/31908/pdfobesityoverweightgastroesophageal reflux diseaseleptinleptin resistance |
| spellingShingle | M A Livzan I V Lapteva T S Krolevets I E Kiselev Specific features of gastroesophageal reflux disease associated with obesity and overweight Терапевтический архив obesity overweight gastroesophageal reflux disease leptin leptin resistance |
| title | Specific features of gastroesophageal reflux disease associated with obesity and overweight |
| title_full | Specific features of gastroesophageal reflux disease associated with obesity and overweight |
| title_fullStr | Specific features of gastroesophageal reflux disease associated with obesity and overweight |
| title_full_unstemmed | Specific features of gastroesophageal reflux disease associated with obesity and overweight |
| title_short | Specific features of gastroesophageal reflux disease associated with obesity and overweight |
| title_sort | specific features of gastroesophageal reflux disease associated with obesity and overweight |
| topic | obesity overweight gastroesophageal reflux disease leptin leptin resistance |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/31908/pdf |
| work_keys_str_mv | AT malivzan specificfeaturesofgastroesophagealrefluxdiseaseassociatedwithobesityandoverweight AT ivlapteva specificfeaturesofgastroesophagealrefluxdiseaseassociatedwithobesityandoverweight AT tskrolevets specificfeaturesofgastroesophagealrefluxdiseaseassociatedwithobesityandoverweight AT iekiselev specificfeaturesofgastroesophagealrefluxdiseaseassociatedwithobesityandoverweight |