Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden Hamsters
Background: to evaluate subcutaneous pancreatic transplantation in an experimentally induced diabetes mellitus in golden hamsters. Methods - many indexes (histological /using two stains, histochemical /using three enzymes, morphometrical and biochemical /blood glucose level) were employed in this as...
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| Format: | Article |
| Language: | English |
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College of Medicine University of Baghdad
2006-10-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1502 |
| _version_ | 1827393631378472960 |
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| author | Mahera N Al-Shaik Huda M Al-Khateeb Salim R Al-Ubaidy |
| author_facet | Mahera N Al-Shaik Huda M Al-Khateeb Salim R Al-Ubaidy |
| author_sort | Mahera N Al-Shaik |
| collection | DOAJ |
| description | Background: to evaluate subcutaneous pancreatic transplantation in an experimentally induced diabetes mellitus in golden hamsters.
Methods - many indexes (histological /using two stains, histochemical /using three enzymes, morphometrical and biochemical /blood glucose level) were employed in this assessment. Alloxan was used as ß-cytotoxic therapy (to induce diabetes mellitus), and cyclophosphamide was employed as immunosuppressive agent.
Results - high rate of success of transplantation (clearly evident by microscopical features of viable endocrine and exocrine tissue of transplanted pancreas and great tissue vascularization, normal enzymatic activities and significant lowering of blood glucose level) were elicited.
Conclusion – subcutaneous pancreatic transplantation should be thank about in treatment of diabetes mellitus. |
| first_indexed | 2024-03-08T17:52:54Z |
| format | Article |
| id | doaj.art-28663dc0b9fb48ef94530019e3698da1 |
| institution | Directory Open Access Journal |
| issn | 0041-9419 2410-8057 |
| language | English |
| last_indexed | 2024-03-08T17:52:54Z |
| publishDate | 2006-10-01 |
| publisher | College of Medicine University of Baghdad |
| record_format | Article |
| series | مجلة كلية الطب |
| spelling | doaj.art-28663dc0b9fb48ef94530019e3698da12024-01-02T06:23:05ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572006-10-01483Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden HamstersMahera N Al-Shaik0Huda M Al-Khateeb1Salim R Al-Ubaidy2Dept. of Anatomy, College of Medicine, Univ. of Baghdad.Dept. of Anatomy, College of Medicine, Univ. of Baghdad.Dept. of Pathology, College of Medicine, Univ. of BaghdadBackground: to evaluate subcutaneous pancreatic transplantation in an experimentally induced diabetes mellitus in golden hamsters. Methods - many indexes (histological /using two stains, histochemical /using three enzymes, morphometrical and biochemical /blood glucose level) were employed in this assessment. Alloxan was used as ß-cytotoxic therapy (to induce diabetes mellitus), and cyclophosphamide was employed as immunosuppressive agent. Results - high rate of success of transplantation (clearly evident by microscopical features of viable endocrine and exocrine tissue of transplanted pancreas and great tissue vascularization, normal enzymatic activities and significant lowering of blood glucose level) were elicited. Conclusion – subcutaneous pancreatic transplantation should be thank about in treatment of diabetes mellitus.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1502Pancreatic transplantation, Diabetes mellitus |
| spellingShingle | Mahera N Al-Shaik Huda M Al-Khateeb Salim R Al-Ubaidy Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden Hamsters مجلة كلية الطب Pancreatic transplantation, Diabetes mellitus |
| title | Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden Hamsters |
| title_full | Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden Hamsters |
| title_fullStr | Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden Hamsters |
| title_full_unstemmed | Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden Hamsters |
| title_short | Subcutaneous Pancreatic Transplantation Shows Success In The Treatment Of Experimentally Induced Diabetes Mellitus In Golden Hamsters |
| title_sort | subcutaneous pancreatic transplantation shows success in the treatment of experimentally induced diabetes mellitus in golden hamsters |
| topic | Pancreatic transplantation, Diabetes mellitus |
| url | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1502 |
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