Risk Factors for Human Infection with Avian Influenza A H5N1, Vietnam, 2004

To evaluate risk factors for human infection with influenza A subtype H5N1, we performed a matched case-control study in Vietnam. We enrolled 28 case-patients who had laboratory-confirmed H5N1 infection during 2004 and 106 age-, sex-, and location-matched control-respondents. Data were analyzed by m...

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Main Authors: Pham Ngoc Dinh, Hoang Thuy Long, Nguyen Thi Kim Tien, Nguyen Tran Hien, Le Thi Quynh Mai, Le Hong Phong, Le Van Tuan, Hoang Van Tan, Nguyen Binh Nguyen, Phan Van Tu, Nguyen Thi Minh Phuong
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2006-12-01
Series:Emerging Infectious Diseases
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Online Access:https://wwwnc.cdc.gov/eid/article/12/12/06-0829_article
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Summary:To evaluate risk factors for human infection with influenza A subtype H5N1, we performed a matched case-control study in Vietnam. We enrolled 28 case-patients who had laboratory-confirmed H5N1 infection during 2004 and 106 age-, sex-, and location-matched control-respondents. Data were analyzed by matched-pair analysis and multivariate conditional logistic regression. Factors that were independently associated with H5N1 infection were preparing sick or dead poultry for consumption <7 days before illness onset (matched odds ratio [OR] 8.99, 95% confidence interval [CI] 0.98–81.99, p = 0.05), having sick or dead poultry in the household <7 days before illness onset (matched OR 4.94, 95% CI 1.21–20.20, p = 0.03), and lack of an indoor water source (matched OR 6.46, 95% CI 1.20–34.81, p = 0.03). Factors not significantly associated with infection were raising healthy poultry, preparing healthy poultry for consumption, and exposure to persons with an acute respiratory illness.
ISSN:1080-6040
1080-6059