Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production o...
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| Format: | Article |
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MDPI AG
2021-11-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/22/11041 |
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| author | Alessandra Quarta Antonio Gaballo Biswajita Pradhan Srimanta Patra Mrutyunjay Jena Andrea Ragusa |
| author_facet | Alessandra Quarta Antonio Gaballo Biswajita Pradhan Srimanta Patra Mrutyunjay Jena Andrea Ragusa |
| author_sort | Alessandra Quarta |
| collection | DOAJ |
| description | Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed. |
| first_indexed | 2024-03-10T05:43:00Z |
| format | Article |
| id | doaj.art-2867d77468ef4318b84906ef0ea4f833 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T05:43:00Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-2867d77468ef4318b84906ef0ea4f8332023-11-22T22:22:46ZengMDPI AGApplied Sciences2076-34172021-11-0111221104110.3390/app112211041Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast CancerAlessandra Quarta0Antonio Gaballo1Biswajita Pradhan2Srimanta Patra3Mrutyunjay Jena4Andrea Ragusa5CNR Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, ItalyCNR Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, ItalyPost Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, IndiaCancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Rourkela 769001, Odisha, IndiaPost Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, IndiaCNR Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, ItalyResveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed.https://www.mdpi.com/2076-3417/11/22/11041resveratrolreactive oxygen speciesbreast cancerantioxidantspolyphenolsoxidative stress |
| spellingShingle | Alessandra Quarta Antonio Gaballo Biswajita Pradhan Srimanta Patra Mrutyunjay Jena Andrea Ragusa Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer Applied Sciences resveratrol reactive oxygen species breast cancer antioxidants polyphenols oxidative stress |
| title | Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
| title_full | Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
| title_fullStr | Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
| title_full_unstemmed | Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
| title_short | Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
| title_sort | beneficial oxidative stress related i trans i resveratrol effects in the treatment and prevention of breast cancer |
| topic | resveratrol reactive oxygen species breast cancer antioxidants polyphenols oxidative stress |
| url | https://www.mdpi.com/2076-3417/11/22/11041 |
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