A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma

Abstract Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. Case Report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of...

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Bibliographic Details
Main Authors: Alexandra Van Brummen, Sarah Jacobs, Shu Feng, Emily Li, Arash J. Amadi
Format: Article
Language:English
Published: Knowledge E 2023-02-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:https://doi.org/10.18502/jovr.v18i1.12733
Description
Summary:Abstract Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. Case Report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO 2 laser-assisted topical steroid application, which resulted in lesion regression. Conclusion: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.
ISSN:2008-2010
2008-322X