A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma
Abstract Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. Case Report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Knowledge E
2023-02-01
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| Series: | Journal of Ophthalmic & Vision Research |
| Subjects: | |
| Online Access: | https://doi.org/10.18502/jovr.v18i1.12733 |
| _version_ | 1811160674660777984 |
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| author | Alexandra Van Brummen Sarah Jacobs Shu Feng Emily Li Arash J. Amadi |
| author_facet | Alexandra Van Brummen Sarah Jacobs Shu Feng Emily Li Arash J. Amadi |
| author_sort | Alexandra Van Brummen |
| collection | DOAJ |
| description | Abstract Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. Case Report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO 2 laser-assisted topical steroid application, which resulted in lesion regression. Conclusion: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control. |
| first_indexed | 2024-04-10T06:02:26Z |
| format | Article |
| id | doaj.art-28692114a30542be98b3a60c402a406a |
| institution | Directory Open Access Journal |
| issn | 2008-2010 2008-322X |
| language | English |
| last_indexed | 2024-04-10T06:02:26Z |
| publishDate | 2023-02-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-28692114a30542be98b3a60c402a406a2023-03-03T07:07:47ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2023-02-011811210.18502/jovr.v18i1.12733jovr.v18i1.12733A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile XanthogranulomaAlexandra Van Brummen0Sarah Jacobs1Shu Feng2Emily Li3Arash J. Amadi4 Department of Ophthalmology, University of Washington, Seattle, WA, USA Department of Ophthalmology, University of Alabama, Birmingham, AL, USA Department of Ophthalmology, University of Washington, Seattle, WA, USA Department of Ophthalmology, University of Washington, Seattle, WA, USA Department of Ophthalmology, University of Washington, Seattle, WA, USAAbstract Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. Case Report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO 2 laser-assisted topical steroid application, which resulted in lesion regression. Conclusion: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.https://doi.org/10.18502/jovr.v18i1.12733co2 laserjuvenile xanthogranulomalaser-assisted steroid delivery |
| spellingShingle | Alexandra Van Brummen Sarah Jacobs Shu Feng Emily Li Arash J. Amadi A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma Journal of Ophthalmic & Vision Research co2 laser juvenile xanthogranuloma laser-assisted steroid delivery |
| title | A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma |
| title_full | A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma |
| title_fullStr | A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma |
| title_full_unstemmed | A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma |
| title_short | A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma |
| title_sort | multifaceted approach to treatment of recalcitrant cutaneous periorbital juvenile xanthogranuloma |
| topic | co2 laser juvenile xanthogranuloma laser-assisted steroid delivery |
| url | https://doi.org/10.18502/jovr.v18i1.12733 |
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