Progressive multifocal leukoencephalopathy
Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by the reactivation of latent JC virus. Since its initial description, there have been changes in its epidemiology, clinical presentation, evolution and prognosis. Some decades ago, it was con...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2008-12-01
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| Series: | Romanian Journal of Neurology |
| Subjects: | |
| Online Access: | https://rjn.com.ro/articles/2008.4/RJN_2008_4_Art-02.pdf |
| _version_ | 1811196687303049216 |
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| author | Rosca Elena Cecilia Mihaela Simu Ruxandra Dana Chirileanu M. Bednar Ovidiu Rosca |
| author_facet | Rosca Elena Cecilia Mihaela Simu Ruxandra Dana Chirileanu M. Bednar Ovidiu Rosca |
| author_sort | Rosca Elena Cecilia |
| collection | DOAJ |
| description | Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by the reactivation of latent JC virus. Since its initial description, there have been changes in its epidemiology, clinical presentation, evolution and prognosis.
Some decades ago, it was considered a rare disease, but now it is a major complication of AIDS and represents an obstacle to the use of promising treatments for autoimmune disorders. Although the survival rate has increased in the last years, still no specific treatment for JC virus is available and further research is needed for a more effective management of the disease. |
| first_indexed | 2024-04-12T01:03:10Z |
| format | Article |
| id | doaj.art-286ce5cd9db644c5ad54ece07be27834 |
| institution | Directory Open Access Journal |
| issn | 1843-8148 2069-6094 |
| language | English |
| last_indexed | 2024-04-12T01:03:10Z |
| publishDate | 2008-12-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Neurology |
| spelling | doaj.art-286ce5cd9db644c5ad54ece07be278342022-12-22T03:54:23ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942008-12-017413113710.37897/RJN.2008.4.2Progressive multifocal leukoencephalopathyRosca Elena Cecilia0Mihaela Simu1Ruxandra Dana Chirileanu2M. Bednar3Ovidiu Rosca4Neurology Department, “Victor Babes” Medicine and Pharmacy University, Timisoara, RomaniaNeurology Department, “Victor Babes” Medicine and Pharmacy University, Timisoara, RomaniaNeurology Department, “Victor Babes” Medicine and Pharmacy University, Timisoara, RomaniaNeurology Department, “Victor Babes” Medicine and Pharmacy University, Timisoara, RomaniaInfectious Diseases Department I, “Victor Babes” Medicine and Pharmacy University, Timisoara, RomaniaProgressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by the reactivation of latent JC virus. Since its initial description, there have been changes in its epidemiology, clinical presentation, evolution and prognosis. Some decades ago, it was considered a rare disease, but now it is a major complication of AIDS and represents an obstacle to the use of promising treatments for autoimmune disorders. Although the survival rate has increased in the last years, still no specific treatment for JC virus is available and further research is needed for a more effective management of the disease.https://rjn.com.ro/articles/2008.4/RJN_2008_4_Art-02.pdfprogressive multifocal leukoencephalopathyjc virusimmunodeficiency |
| spellingShingle | Rosca Elena Cecilia Mihaela Simu Ruxandra Dana Chirileanu M. Bednar Ovidiu Rosca Progressive multifocal leukoencephalopathy Romanian Journal of Neurology progressive multifocal leukoencephalopathy jc virus immunodeficiency |
| title | Progressive multifocal leukoencephalopathy |
| title_full | Progressive multifocal leukoencephalopathy |
| title_fullStr | Progressive multifocal leukoencephalopathy |
| title_full_unstemmed | Progressive multifocal leukoencephalopathy |
| title_short | Progressive multifocal leukoencephalopathy |
| title_sort | progressive multifocal leukoencephalopathy |
| topic | progressive multifocal leukoencephalopathy jc virus immunodeficiency |
| url | https://rjn.com.ro/articles/2008.4/RJN_2008_4_Art-02.pdf |
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