Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States

Lyme disease, often characterized as a readily treatable infection, can be a debilitating and expensive illness, especially when patients remain symptomatic following therapy for early disease. Identifying and promoting highly effective therapeutic interventions for US patients with erythema migrans...

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Main Author: Elizabeth L. Maloney
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/7/754
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author Elizabeth L. Maloney
author_facet Elizabeth L. Maloney
author_sort Elizabeth L. Maloney
collection DOAJ
description Lyme disease, often characterized as a readily treatable infection, can be a debilitating and expensive illness, especially when patients remain symptomatic following therapy for early disease. Identifying and promoting highly effective therapeutic interventions for US patients with erythema migrans (EM) rashes that return them to their pre-infection health status should be a priority. The recently released treatment recommendations by the Infectious Diseases Society of America/American Academy of Neurology/American College of Rheumatology (IDSA/AAN/ACR) for the treatment of US patients fall short of that goal. This paper reviews the US trial evidence regarding EM rashes, discusses the shortcomings of the IDSA/AAN/ACR recommendations in light of that evidence and offers evidence-based, patient-centered strategies for managing patients with erythema migrans lesions.
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spelling doaj.art-2873707038bc4b518be075ef067ef3772023-11-22T01:11:03ZengMDPI AGAntibiotics2079-63822021-06-0110775410.3390/antibiotics10070754Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United StatesElizabeth L. Maloney0Partnership for Tick-Borne Diseases Education, P.O. Box 84, Wyoming, MN 55092, USALyme disease, often characterized as a readily treatable infection, can be a debilitating and expensive illness, especially when patients remain symptomatic following therapy for early disease. Identifying and promoting highly effective therapeutic interventions for US patients with erythema migrans (EM) rashes that return them to their pre-infection health status should be a priority. The recently released treatment recommendations by the Infectious Diseases Society of America/American Academy of Neurology/American College of Rheumatology (IDSA/AAN/ACR) for the treatment of US patients fall short of that goal. This paper reviews the US trial evidence regarding EM rashes, discusses the shortcomings of the IDSA/AAN/ACR recommendations in light of that evidence and offers evidence-based, patient-centered strategies for managing patients with erythema migrans lesions.https://www.mdpi.com/2079-6382/10/7/754erythema migransamoxicillincefuroximedoxycyclinetreatmentLyme disease
spellingShingle Elizabeth L. Maloney
Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States
Antibiotics
erythema migrans
amoxicillin
cefuroxime
doxycycline
treatment
Lyme disease
title Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States
title_full Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States
title_fullStr Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States
title_full_unstemmed Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States
title_short Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States
title_sort evidence based patient centered treatment of erythema migrans in the united states
topic erythema migrans
amoxicillin
cefuroxime
doxycycline
treatment
Lyme disease
url https://www.mdpi.com/2079-6382/10/7/754
work_keys_str_mv AT elizabethlmaloney evidencebasedpatientcenteredtreatmentoferythemamigransintheunitedstates