LITHIUM INTOXICATION IN INFECTIOUS CONTEXT OF A PATIENT ON CHRONIC LITHIUM THERAPY
Introduction. In the history of his usage, by the 1850`s, Lithium was first used for the treatment of the gout. As mania and melancholia were included in the same diagnostic group, Lithium started to be used for the treatment of mental disorders. Nowadays, Lithium is still used in the bipolar diso...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2017-03-01
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| Series: | Romanian Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | https://revistemedicale.amaltea.ro/Romanian_Journal_of_INFECTIOUS_DISEASES/Revista_Romana_de_BOLI_INFECTIOASE-2017-Nr.1/RJID_2017_1_EN_Art-05.pdf |
| Summary: | Introduction. In the history of his usage, by the 1850`s, Lithium was first used for the treatment of the gout.
As mania and melancholia were included in the same diagnostic group, Lithium started to be used for the
treatment of mental disorders. Nowadays, Lithium is still used in the bipolar disorder and as adjuvant in depression, schizophrenia, schizoaffective disorder and for the control of child aggressiveness.
Methods and objective. Reporting a case of Lithium Intoxication in a patient with infection and chronic treatment with Lithium Carbonate.
Objectives. Reporting a case of Lithium Intoxication in a patient with streptococcal angina infection and
chronic treatment with Lithium Carbonate.
Conclusion. Lithium intoxication may be rare in medical practice because of rare usage of Lithium therapy
and strict monitorization of serum concentration. In this case, the tonsillar infectious accompanied by fever,
impossibility of proper oral hydration and impairment of renal functions were the initial trigger of the pathological mechanism of intoxication syndrome. Secondary, the excretion of Lithium decreased and the low serum
volume led to high blood concentration of Lithium. Later on, the gastrointenstinal impairment which appeared
slowly added to the vicious circle which involved hydration, excretion and serum concentration of Lithium
producing and intoxication syndrome. |
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| ISSN: | 1454-3389 2069-6051 |