Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy
We report the case of a primary nasopharyngeal interdigitating dendritic cell tumor (IDDCT). A 25-year old male presented with bilateral decreased hearing, double vision, and ataxia. Flexible nasopharyngoscopy reviewed a large mass obstructing and filling the entire nasopharynx. MRI and PET-CT confi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2010-03-01
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| Series: | Rare Tumors |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/1618 |
| _version_ | 1818058959640068096 |
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| author | Paul W. Read John B. Cousar Michael G. Douvas James F. Reibel Asal N. Shoushtari Randell L. Woodford Neal E. Dunlap |
| author_facet | Paul W. Read John B. Cousar Michael G. Douvas James F. Reibel Asal N. Shoushtari Randell L. Woodford Neal E. Dunlap |
| author_sort | Paul W. Read |
| collection | DOAJ |
| description | We report the case of a primary nasopharyngeal interdigitating dendritic cell tumor (IDDCT). A 25-year old male presented with bilateral decreased hearing, double vision, and ataxia. Flexible nasopharyngoscopy reviewed a large mass obstructing and filling the entire nasopharynx. MRI and PET-CT confirmed the presence of the primary tumor and demonstrated bilateral cervical lymphadenopathy. Biopsy of the nasopharynx revealed a hematolymphoid neoplasm with dendritic cell differentiation, most consistent with an IDDCT. The lesion was unresectable. The patient was treated with definitive radiotherapy to 66 Gy to the primary tumor and 50 Gy to the bilateral cervical lymphatics using an IMRT technique. A complete response was achieved and the patient remains disease free at the primary site 23 months after completion of radiotherapy. |
| first_indexed | 2024-12-10T13:08:55Z |
| format | Article |
| id | doaj.art-287586ba69444c75a947bac4923128aa |
| institution | Directory Open Access Journal |
| issn | 2036-3603 2036-3613 |
| language | English |
| last_indexed | 2024-12-10T13:08:55Z |
| publishDate | 2010-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-287586ba69444c75a947bac4923128aa2022-12-22T01:47:44ZengSAGE PublishingRare Tumors2036-36032036-36132010-03-0121e9e910.4081/rt.2010.e9Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapyPaul W. ReadJohn B. CousarMichael G. DouvasJames F. ReibelAsal N. ShoushtariRandell L. WoodfordNeal E. DunlapWe report the case of a primary nasopharyngeal interdigitating dendritic cell tumor (IDDCT). A 25-year old male presented with bilateral decreased hearing, double vision, and ataxia. Flexible nasopharyngoscopy reviewed a large mass obstructing and filling the entire nasopharynx. MRI and PET-CT confirmed the presence of the primary tumor and demonstrated bilateral cervical lymphadenopathy. Biopsy of the nasopharynx revealed a hematolymphoid neoplasm with dendritic cell differentiation, most consistent with an IDDCT. The lesion was unresectable. The patient was treated with definitive radiotherapy to 66 Gy to the primary tumor and 50 Gy to the bilateral cervical lymphatics using an IMRT technique. A complete response was achieved and the patient remains disease free at the primary site 23 months after completion of radiotherapy.http://www.pagepress.org/journals/index.php/rt/article/view/1618hematolymphoid neoplasmIMRTIDDCTextranodal |
| spellingShingle | Paul W. Read John B. Cousar Michael G. Douvas James F. Reibel Asal N. Shoushtari Randell L. Woodford Neal E. Dunlap Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy Rare Tumors hematolymphoid neoplasm IMRT IDDCT extranodal |
| title | Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy |
| title_full | Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy |
| title_fullStr | Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy |
| title_full_unstemmed | Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy |
| title_short | Primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy |
| title_sort | primary nasopharyngeal interdigitating dendritic cell tumor presentation and response to radiation therapy |
| topic | hematolymphoid neoplasm IMRT IDDCT extranodal |
| url | http://www.pagepress.org/journals/index.php/rt/article/view/1618 |
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