An evolved ribosome-inactivating protein targets and kills human melanoma cells <it>in vitro </it>and <it>in vivo</it>

An evolved ribosome-inactivating protein targets and kills human melanoma cells <it>in vitro </it>and <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Few treatment options exist for patients with metastatic melanoma, resulting in poor prognosis. One standard treatment, dacarbazine (DTIC), shows low response rates ranging from 15 to 25 percent with an 8-month median survival time....

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Bibliographic Details
Main Authors: Green David E, Kiarash Reza, Wei Xin, Perampalam Subodini, Revers Leigh, Cheung Melissa C, Abdul-Wahid Aws, Gariépy Jean
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/28

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