Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“

Skull base osteomyelitis is a rare life-threatening condition seen most commonly in immunocompromised patients, generally caused by ear infections with commonest causative organism being Pseudomonas Aeruginosa. Atypical skull base osteomyelitis commonly involves sphenoid and occipital bones. Patient...

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Main Authors: Sanjay Kumar, Ashok Kumar, Hrishikesh Gadhavi, Vikas Maheshwari
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Interdisciplinary Neurosurgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214751920303777
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author Sanjay Kumar
Ashok Kumar
Hrishikesh Gadhavi
Vikas Maheshwari
author_facet Sanjay Kumar
Ashok Kumar
Hrishikesh Gadhavi
Vikas Maheshwari
author_sort Sanjay Kumar
collection DOAJ
description Skull base osteomyelitis is a rare life-threatening condition seen most commonly in immunocompromised patients, generally caused by ear infections with commonest causative organism being Pseudomonas Aeruginosa. Atypical skull base osteomyelitis commonly involves sphenoid and occipital bones. Patient generally presents with headache as chief complaint & later may develop complications in the form of cranial neuropathies. Clinical diagnosis is difficult due to subtle & non-specific findings therefore, clinician has to have a high index of suspicion & low threshold for investigations. Early recognition of characteristic imaging findings is important for correct & timely diagnosis to differentiate it from skull base malignancy and to decrease the morbidity. Prompt diagnosis by early tissue sampling and appropriate treatment are of utmost importance to prevent or limit further complications such as intracranial extension, empyema, or death. Monitoring of the ESR has prognostic importance that can help to guide the duration of antibiotic therapy. We report a rare case of extensive skull base atypical osteomyelitis in an immunocompetent person without preceding infection. He was diagnosed promptly, managed surgically with debridement of abscess, drainage of pus and recovered well without any neurological deficits. This case is being reported because we could not find any similar case after an extensive search of the literature and the complete recovery made by the patient.
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spelling doaj.art-28796904f80746cca5f75b77a9d117792022-12-21T21:56:05ZengElsevierInterdisciplinary Neurosurgery2214-75192021-06-0124100816Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“Sanjay Kumar0Ashok Kumar1Hrishikesh Gadhavi2Vikas Maheshwari3Department of Neurosurgery, Command Hospital (Southern Command), Pune 411040, India; Corresponding author at: Department of Neurosurgery, Command Hospital (Southern Command), Pune 411040, India.SR Neurosurgery, Department of Neurosurgery, Command Hospital (Southern Command), Pune 411040, IndiaDepartment of Neurosurgery, Command Hospital (Southern Command), Pune 411040, IndiaSR Neurosurgery, Department of Neurosurgery, Command Hospital (Southern Command), Pune 411040, IndiaSkull base osteomyelitis is a rare life-threatening condition seen most commonly in immunocompromised patients, generally caused by ear infections with commonest causative organism being Pseudomonas Aeruginosa. Atypical skull base osteomyelitis commonly involves sphenoid and occipital bones. Patient generally presents with headache as chief complaint & later may develop complications in the form of cranial neuropathies. Clinical diagnosis is difficult due to subtle & non-specific findings therefore, clinician has to have a high index of suspicion & low threshold for investigations. Early recognition of characteristic imaging findings is important for correct & timely diagnosis to differentiate it from skull base malignancy and to decrease the morbidity. Prompt diagnosis by early tissue sampling and appropriate treatment are of utmost importance to prevent or limit further complications such as intracranial extension, empyema, or death. Monitoring of the ESR has prognostic importance that can help to guide the duration of antibiotic therapy. We report a rare case of extensive skull base atypical osteomyelitis in an immunocompetent person without preceding infection. He was diagnosed promptly, managed surgically with debridement of abscess, drainage of pus and recovered well without any neurological deficits. This case is being reported because we could not find any similar case after an extensive search of the literature and the complete recovery made by the patient.http://www.sciencedirect.com/science/article/pii/S2214751920303777Skull base osteomyelitis (SBO)Atypical osteomyelitisAntitubercular Treatment (ATT)Immunocompetent
spellingShingle Sanjay Kumar
Ashok Kumar
Hrishikesh Gadhavi
Vikas Maheshwari
Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“
Interdisciplinary Neurosurgery
Skull base osteomyelitis (SBO)
Atypical osteomyelitis
Antitubercular Treatment (ATT)
Immunocompetent
title Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“
title_full Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“
title_fullStr Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“
title_full_unstemmed Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“
title_short Tubercular skull base osteomyelitis in an immunocompetent individual: A rare entity“
title_sort tubercular skull base osteomyelitis in an immunocompetent individual a rare entity
topic Skull base osteomyelitis (SBO)
Atypical osteomyelitis
Antitubercular Treatment (ATT)
Immunocompetent
url http://www.sciencedirect.com/science/article/pii/S2214751920303777
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AT hrishikeshgadhavi tubercularskullbaseosteomyelitisinanimmunocompetentindividualarareentity
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