Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination
Key clinical message In in vitro fertilization (IVF), laser offers several advantages. In this study, we employed laser to eliminate the zona pellucida of a contaminated embryo. This approach helps to rescue embryo with bacterial contamination, and improve embryo‐endometrium interaction. Abstract To...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-02-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.8483 |
| _version_ | 1797291547163623424 |
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| author | Son Truong Dang Huy Phuong Tran Tuong Nguyen Ho Loc Thai Ly Tuyet Thi‐Diem Hoang Trang Nguyen‐Khanh Huynh Anh Tuan Do Thuan Duc Nguyen Phuong Thi Dao |
| author_facet | Son Truong Dang Huy Phuong Tran Tuong Nguyen Ho Loc Thai Ly Tuyet Thi‐Diem Hoang Trang Nguyen‐Khanh Huynh Anh Tuan Do Thuan Duc Nguyen Phuong Thi Dao |
| author_sort | Son Truong Dang |
| collection | DOAJ |
| description | Key clinical message In in vitro fertilization (IVF), laser offers several advantages. In this study, we employed laser to eliminate the zona pellucida of a contaminated embryo. This approach helps to rescue embryo with bacterial contamination, and improve embryo‐endometrium interaction. Abstract To present a case report on the removal of a contaminated zona pellucida from an embryo of patient with a history of recurrent implantation failure (RIF), which was followed by a successful live birth. We present the case of a 34‐year‐old patient with a history of 3 years of infertility who underwent in vitro fertilization. During the culture process, the embryos became contaminated, leading to three failed implantations. Despite the aneuploidy of the embryo and the implementation of a washing technique, the contamination persisted. In the final attempt, the contaminated zona pellucida was successfully removed using laser, followed by embryo transfer, resulting in a live birth. We provided detailed clinical information, including patient demographics, infertility history, ovarian response, evidence of bacterial contamination, embryo development, treatment protocols, and outcomes. Laser excision of the zona pellucida is a safe and effective method for addressing bacterial infection in embryos. |
| first_indexed | 2024-03-07T19:38:19Z |
| format | Article |
| id | doaj.art-2886115488d7428581ccc5aa0386fbf5 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-07T19:38:19Z |
| publishDate | 2024-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-2886115488d7428581ccc5aa0386fbf52024-02-29T07:13:20ZengWileyClinical Case Reports2050-09042024-02-01122n/an/a10.1002/ccr3.8483Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contaminationSon Truong Dang0Huy Phuong Tran1Tuong Nguyen Ho2Loc Thai Ly3Tuyet Thi‐Diem Hoang4Trang Nguyen‐Khanh Huynh5Anh Tuan Do6Thuan Duc Nguyen7Phuong Thi Dao8HP Fertility Hai Phong International Hospital of Obstetrics and Pediatrics VietnamInfertility Department Hung Vuong Hospital Ho Chi Minh City VietnamTaipei Fertility Center Taipei TaiwanInfertility Department Hung Vuong Hospital Ho Chi Minh City VietnamInfertility Department Hung Vuong Hospital Ho Chi Minh City VietnamDepartment of Obstetrics and Gynaecology Pham Ngoc Thach University of Medicine Ho Chi Minh City VietnamHP Fertility Hai Phong International Hospital of Obstetrics and Pediatrics VietnamHP Fertility Hai Phong International Hospital of Obstetrics and Pediatrics VietnamHP Fertility Hai Phong International Hospital of Obstetrics and Pediatrics VietnamKey clinical message In in vitro fertilization (IVF), laser offers several advantages. In this study, we employed laser to eliminate the zona pellucida of a contaminated embryo. This approach helps to rescue embryo with bacterial contamination, and improve embryo‐endometrium interaction. Abstract To present a case report on the removal of a contaminated zona pellucida from an embryo of patient with a history of recurrent implantation failure (RIF), which was followed by a successful live birth. We present the case of a 34‐year‐old patient with a history of 3 years of infertility who underwent in vitro fertilization. During the culture process, the embryos became contaminated, leading to three failed implantations. Despite the aneuploidy of the embryo and the implementation of a washing technique, the contamination persisted. In the final attempt, the contaminated zona pellucida was successfully removed using laser, followed by embryo transfer, resulting in a live birth. We provided detailed clinical information, including patient demographics, infertility history, ovarian response, evidence of bacterial contamination, embryo development, treatment protocols, and outcomes. Laser excision of the zona pellucida is a safe and effective method for addressing bacterial infection in embryos.https://doi.org/10.1002/ccr3.8483contaminated embryoembryo transferIVFrecurrent implantation failurezona pellucida removal |
| spellingShingle | Son Truong Dang Huy Phuong Tran Tuong Nguyen Ho Loc Thai Ly Tuyet Thi‐Diem Hoang Trang Nguyen‐Khanh Huynh Anh Tuan Do Thuan Duc Nguyen Phuong Thi Dao Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination Clinical Case Reports contaminated embryo embryo transfer IVF recurrent implantation failure zona pellucida removal |
| title | Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination |
| title_full | Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination |
| title_fullStr | Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination |
| title_full_unstemmed | Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination |
| title_short | Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination |
| title_sort | zona pellucida removal resulted in a successful live birth report on a case with recurrent implantation failure due to embryonic bacteria contamination |
| topic | contaminated embryo embryo transfer IVF recurrent implantation failure zona pellucida removal |
| url | https://doi.org/10.1002/ccr3.8483 |
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