blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil
Previous analysis of Pseudomonas aeruginosa class-1 integrons from Rio de Janeiro, Brazil, revealed the blaGES gene in one isolate. We screened isolates of two widespread PFGE genotypes, A and B, at a public hospital in Rio, for the presence of blaGES. The gene was detected in all seven P. aeruginos...
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Elsevier
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Series: | Brazilian Journal of Infectious Diseases |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400007&lng=en&tlng=en |
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author | Flávia L. P. C. Pellegrino Kátia R. Netto-dos Santos Lee W. Riley Beatriz M. Moreira |
author_facet | Flávia L. P. C. Pellegrino Kátia R. Netto-dos Santos Lee W. Riley Beatriz M. Moreira |
author_sort | Flávia L. P. C. Pellegrino |
collection | DOAJ |
description | Previous analysis of Pseudomonas aeruginosa class-1 integrons from Rio de Janeiro, Brazil, revealed the blaGES gene in one isolate. We screened isolates of two widespread PFGE genotypes, A and B, at a public hospital in Rio, for the presence of blaGES. The gene was detected in all seven P. aeruginosa isolates belonging to genotype B. Three of the seven genotype-B isolates were resistant to amikacin, aztreonam, ceftazidime, cefepime, ciprofloxacin, gentamicin, imipenem, meropenem, piperacillin-tazobactam and ticarcillin-clavulanic acid. The other four isolates were resistant to all these agents, except gentamicin, imipenem, meropenem and piperacillin-tazobactam. A synergistic effect between ceftazidime and imipenem or clavulanic acid suggested the production of GES-type ESBL. |
first_indexed | 2024-12-12T11:54:01Z |
format | Article |
id | doaj.art-28877a954ee64754b058a5dbb8ee3cb9 |
institution | Directory Open Access Journal |
issn | 1678-4391 |
language | English |
last_indexed | 2024-12-12T11:54:01Z |
publisher | Elsevier |
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series | Brazilian Journal of Infectious Diseases |
spelling | doaj.art-28877a954ee64754b058a5dbb8ee3cb92022-12-22T00:25:14ZengElsevierBrazilian Journal of Infectious Diseases1678-439110425125310.1590/S1413-86702006000400007S1413-86702006000400007blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, BrazilFlávia L. P. C. Pellegrino0Kátia R. Netto-dos Santos1Lee W. Riley2Beatriz M. Moreira3Universidade Federal do Rio de JaneiroUniversidade Federal do Rio de JaneiroSchool of Public HealthUniversidade Federal do Rio de JaneiroPrevious analysis of Pseudomonas aeruginosa class-1 integrons from Rio de Janeiro, Brazil, revealed the blaGES gene in one isolate. We screened isolates of two widespread PFGE genotypes, A and B, at a public hospital in Rio, for the presence of blaGES. The gene was detected in all seven P. aeruginosa isolates belonging to genotype B. Three of the seven genotype-B isolates were resistant to amikacin, aztreonam, ceftazidime, cefepime, ciprofloxacin, gentamicin, imipenem, meropenem, piperacillin-tazobactam and ticarcillin-clavulanic acid. The other four isolates were resistant to all these agents, except gentamicin, imipenem, meropenem and piperacillin-tazobactam. A synergistic effect between ceftazidime and imipenem or clavulanic acid suggested the production of GES-type ESBL.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400007&lng=en&tlng=enPseudomonas aeruginosablaGES, antibioticspublic hospitalRio de JaneiroBrazil |
spellingShingle | Flávia L. P. C. Pellegrino Kátia R. Netto-dos Santos Lee W. Riley Beatriz M. Moreira blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil Brazilian Journal of Infectious Diseases Pseudomonas aeruginosa blaGES, antibiotics public hospital Rio de Janeiro Brazil |
title | blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil |
title_full | blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil |
title_fullStr | blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil |
title_full_unstemmed | blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil |
title_short | blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil |
title_sort | blages carrying pseudomonas aeruginosa isolates from a public hospital in rio de janeiro brazil |
topic | Pseudomonas aeruginosa blaGES, antibiotics public hospital Rio de Janeiro Brazil |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400007&lng=en&tlng=en |
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