Biotinylated Polymer-Ruthenium Conjugates: In Vitro and In Vivo Studies in a Triple-Negative Breast Cancer Model

Biotinylated Polymer-Ruthenium Conjugates: In Vitro and In Vivo Studies in a Triple-Negative Breast Cancer Model

The need for new therapeutic approaches for triple-negative breast cancer is a clinically relevant problem that needs to be solved. Using a multi-targeting approach to enhance cancer cell uptake, we synthesized a new family of ruthenium(II) organometallic complexes envisaging simultaneous active and...

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Bibliographic Details
Main Authors: Leonor Côrte-Real, Ana Rita Brás, Adhan Pilon, Nuno Mendes, Ana Sofia Ribeiro, Tiago D. Martins, José Paulo S. Farinha, M. Conceição Oliveira, Fátima Gärtner, M. Helena Garcia, Ana Preto, Andreia Valente
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
ruthenium-cyclopentadienyl compounds
triple negative breast cancer
active-targeting
Online Access:https://www.mdpi.com/1999-4923/14/7/1388

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