Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy

Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy

Gastrointestinal tumors, including pancreatic and colorectal cancers, represent one of the greatest public health issues worldwide, leading to a million global deaths. Recent research demonstrated that the human heavy chain ferritin (HFt) can encapsulate different types of drugs in its cavity and ca...

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Bibliographic Details
Main Authors: Elisabetta Falvo, Alessandro Arcovito, Giamaica Conti, Giuseppe Cipolla, Martina Pitea, Veronica Morea, Verena Damiani, Gianluca Sala, Giulio Fracasso, Pierpaolo Ceci
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
nanomedicine
human ferritin
gastrointestinal tumors
non-camptothecin topoisomerase I inhibitors
drug-delivery
CD71
Online Access:https://www.mdpi.com/1999-4923/12/10/992

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