HIV-2-Infected Macrophages Produce and Accumulate Poorly Infectious Viral Particles

HIV-2-Infected Macrophages Produce and Accumulate Poorly Infectious Viral Particles

A significant proportion of HIV-2-infected patients exhibit natural virological control that is generally absent from HIV-1-infected patients. Along with CD4+ T cells, HIV-1 targets macrophages which may contribute to viral spreading and the latent reservoir. We have studied the relationship between...

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Bibliographic Details
Main Authors: Ester Gea-Mallorquí, Laurent Zablocki-Thomas, Mathieu Maurin, Mabel Jouve, Vasco Rodrigues, Nicolas Ruffin, Philippe Benaroch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
macrophages
HIV-2
viral assembly
virus-containing compartment
restriction factors
HIV transmission to T cells
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01603/full

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