Machine learning model for sequence-driven DNA G-quadruplex formation
Abstract We describe a sequence-based computational model to predict DNA G-quadruplex (G4) formation. The model was developed using large-scale machine learning from an extensive experimental G4-formation dataset, recently obtained for the human genome via G4-seq methodology. Our model differentiate...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-11-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-14017-4 |