Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study

Abstract Background Digital cognitive behavior therapy for insomnia (dCBT-I) is an effective treatment in alleviating insomnia. This study examined the effect of dCBT-I for improving sleep quality in patients with insomnia complaints from a clinical population in a real-world setting. Methods The st...

Full description

Bibliographic Details
Main Authors: Sugai Liang, Hongjing Mao, Jingyun Yang, Wei Deng, Bo Cao, Zhenghe Yu, Lili Yang, You Xu, Nannan Hu, Wenjuan Liu, Andrew J. Greenshaw, Tao Li
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-022-04411-2
_version_ 1811178973243113472
author Sugai Liang
Hongjing Mao
Jingyun Yang
Wei Deng
Bo Cao
Zhenghe Yu
Lili Yang
You Xu
Nannan Hu
Wenjuan Liu
Andrew J. Greenshaw
Tao Li
author_facet Sugai Liang
Hongjing Mao
Jingyun Yang
Wei Deng
Bo Cao
Zhenghe Yu
Lili Yang
You Xu
Nannan Hu
Wenjuan Liu
Andrew J. Greenshaw
Tao Li
author_sort Sugai Liang
collection DOAJ
description Abstract Background Digital cognitive behavior therapy for insomnia (dCBT-I) is an effective treatment in alleviating insomnia. This study examined the effect of dCBT-I for improving sleep quality in patients with insomnia complaints from a clinical population in a real-world setting. Methods The study included 6,002 patients aged 18 years and above with primary complaints of dissatisfying sleep from a sleep clinic in a psychiatric hospital from November 2016 to April 2021. Patients were diagnosed with insomnia, anxiety disorders, or anxiety comorbid with insomnia or depression according to ICD-10. A mobile app was developed for self-reported assessment and delivering dCBT-I interventions and treatment prescriptions to participants. The primary outcome was change in global sleep quality measured by the Pittsburgh Sleep Quality Index (PSQI). At 8- and 12-week follow-up, 509 patients were reassessed. Data were analyzed with non-parametric tests for repeated measures. Results Patients treated with dCBT-I monotherapy were younger, with a more frequent family history of insomnia compared to those with medication monotherapy and those with combined dCBT-I and medication therapy. Improvements of sleep quality from baseline to 8-week follow-up were significant in each treatment type. Compared to 8-week follow-up, PSQI scores at 12-week were significantly decreased in the depression group receiving combined therapy and in the anxiety group treated with dCBT-I monotherapy and with combined therapy. A time-by-treatment interaction was detected in anxiety patients indicating differential reduction in PSQI scores over time between different treatment options. Conclusion The current findings suggest dCBT-I is a practical and effective approach for lessening insomnia symptoms, especially for patients with anxiety symptoms suggesting with a more extended intervention period (i.e., 12 weeks). Trial registration Chinese Clinical Trial Registry (ChiCTR1900022699).
first_indexed 2024-04-11T06:28:04Z
format Article
id doaj.art-28948e93240a4442ab2dd9a70f99b04e
institution Directory Open Access Journal
issn 1471-244X
language English
last_indexed 2024-04-11T06:28:04Z
publishDate 2022-12-01
publisher BMC
record_format Article
series BMC Psychiatry
spelling doaj.art-28948e93240a4442ab2dd9a70f99b04e2022-12-22T04:40:16ZengBMCBMC Psychiatry1471-244X2022-12-012211910.1186/s12888-022-04411-2Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world studySugai Liang0Hongjing Mao1Jingyun Yang2Wei Deng3Bo Cao4Zhenghe Yu5Lili Yang6You Xu7Nannan Hu8Wenjuan Liu9Andrew J. Greenshaw10Tao Li11Affiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineDepartment of Neurological Sciences, Rush University Medical CenterAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineDepartment of Psychiatry, University of AlbertaAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineDepartment of Psychiatry, University of AlbertaAffiliated Mental Health Centre & Hangzhou Seventh People’s Hospital, Zhejiang University School of MedicineAbstract Background Digital cognitive behavior therapy for insomnia (dCBT-I) is an effective treatment in alleviating insomnia. This study examined the effect of dCBT-I for improving sleep quality in patients with insomnia complaints from a clinical population in a real-world setting. Methods The study included 6,002 patients aged 18 years and above with primary complaints of dissatisfying sleep from a sleep clinic in a psychiatric hospital from November 2016 to April 2021. Patients were diagnosed with insomnia, anxiety disorders, or anxiety comorbid with insomnia or depression according to ICD-10. A mobile app was developed for self-reported assessment and delivering dCBT-I interventions and treatment prescriptions to participants. The primary outcome was change in global sleep quality measured by the Pittsburgh Sleep Quality Index (PSQI). At 8- and 12-week follow-up, 509 patients were reassessed. Data were analyzed with non-parametric tests for repeated measures. Results Patients treated with dCBT-I monotherapy were younger, with a more frequent family history of insomnia compared to those with medication monotherapy and those with combined dCBT-I and medication therapy. Improvements of sleep quality from baseline to 8-week follow-up were significant in each treatment type. Compared to 8-week follow-up, PSQI scores at 12-week were significantly decreased in the depression group receiving combined therapy and in the anxiety group treated with dCBT-I monotherapy and with combined therapy. A time-by-treatment interaction was detected in anxiety patients indicating differential reduction in PSQI scores over time between different treatment options. Conclusion The current findings suggest dCBT-I is a practical and effective approach for lessening insomnia symptoms, especially for patients with anxiety symptoms suggesting with a more extended intervention period (i.e., 12 weeks). Trial registration Chinese Clinical Trial Registry (ChiCTR1900022699).https://doi.org/10.1186/s12888-022-04411-2Digital cognitive behavior therapy (dCBT)InsomniaDepressionAnxietySleep quality
spellingShingle Sugai Liang
Hongjing Mao
Jingyun Yang
Wei Deng
Bo Cao
Zhenghe Yu
Lili Yang
You Xu
Nannan Hu
Wenjuan Liu
Andrew J. Greenshaw
Tao Li
Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study
BMC Psychiatry
Digital cognitive behavior therapy (dCBT)
Insomnia
Depression
Anxiety
Sleep quality
title Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study
title_full Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study
title_fullStr Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study
title_full_unstemmed Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study
title_short Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study
title_sort digital cognitive behavior therapy for insomnia improving sleep quality a real world study
topic Digital cognitive behavior therapy (dCBT)
Insomnia
Depression
Anxiety
Sleep quality
url https://doi.org/10.1186/s12888-022-04411-2
work_keys_str_mv AT sugailiang digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT hongjingmao digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT jingyunyang digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT weideng digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT bocao digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT zhengheyu digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT liliyang digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT youxu digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT nannanhu digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT wenjuanliu digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT andrewjgreenshaw digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy
AT taoli digitalcognitivebehaviortherapyforinsomniaimprovingsleepqualityarealworldstudy