Memory B-cells are enriched in the blood of patients with acute Buruli ulcer disease: a prospective observational study

Memory B-cells are enriched in the blood of patients with acute Buruli ulcer disease: a prospective observational study

Abstract Background Buruli ulcer disease (BUD) caused by Mycobacterium (M.) ulcerans is characterized by necrotic skin lesions. As for other mycobacterial infections, e.g., tuberculosis, the immune response is important for host protection. B-cells may play a role in antimycobacterial immunity but s...

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Bibliographic Details
Main Authors: Jonathan Kofi Adjei, Wilfred Aniagyei, Ernest Adankwah, Julia Seyfarth, Ertan Mayatepek, Daniel Antwi Berko, Nancy Ackam, Max Efui Annani-Akollor, Samuel Asamoah Sakyi, Yaw Ampem Amoako, Dorcas Owusu, Marc Jacobsen, Richard Odame Phillips
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Infectious Diseases
Subjects:
B-cell subsets
Buruli ulcer
Mycobacterium ulcerans
Biomarker
Online Access:https://doi.org/10.1186/s12879-023-08370-1

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