Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss Mice
Abdominal angiostrongylosis is a nematode infection of wild rodents. Human infection may result in severe abdominal disease and has been reported from several countries in the Americas. The domestic mouse, Mus musculus, has not been found with natural infection and, like other urban rodents, should...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
1998-03-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000200026 |
| _version_ | 1797756694387752960 |
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| author | Cibele Canali Aline H Goulart Carlos Graeff-Teixeira |
| author_facet | Cibele Canali Aline H Goulart Carlos Graeff-Teixeira |
| author_sort | Cibele Canali |
| collection | DOAJ |
| description | Abdominal angiostrongylosis is a nematode infection of wild rodents. Human infection may result in severe abdominal disease and has been reported from several countries in the Americas. The domestic mouse, Mus musculus, has not been found with natural infection and, like other urban rodents, should not be considered a natural host for Angiostrongylus costaricensis. Quantification of parasitic forms released for transmission may better express the coevolutionary status in parasite-host relationship. With this objective, five groups of experimentally infected Swiss mice were followed for up to 155 days post-infection (PI) days and the quantification of first stage larvae (L1) output revealed: an irregular elimination of L1 and a huge variation in the patency period (1 to 114 days) and in the number of L1 eliminated daily by individual animals (1 to 6340 L1/g). Overall mortality was 72% (range: 28% to 100%) at seven weeks PI. In conclusion, abdominal angiostrongylosis in M. musculus presents high mortality and a very variable and irregular elimination of L1 in feces. |
| first_indexed | 2024-03-12T18:05:11Z |
| format | Article |
| id | doaj.art-2899992c36c14de3b7519bebc31a2e35 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:05:11Z |
| publishDate | 1998-03-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-2899992c36c14de3b7519bebc31a2e352023-08-02T09:28:31ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601998-03-0193226910.1590/S0074-02761998000200026Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss MiceCibele CanaliAline H GoulartCarlos Graeff-TeixeiraAbdominal angiostrongylosis is a nematode infection of wild rodents. Human infection may result in severe abdominal disease and has been reported from several countries in the Americas. The domestic mouse, Mus musculus, has not been found with natural infection and, like other urban rodents, should not be considered a natural host for Angiostrongylus costaricensis. Quantification of parasitic forms released for transmission may better express the coevolutionary status in parasite-host relationship. With this objective, five groups of experimentally infected Swiss mice were followed for up to 155 days post-infection (PI) days and the quantification of first stage larvae (L1) output revealed: an irregular elimination of L1 and a huge variation in the patency period (1 to 114 days) and in the number of L1 eliminated daily by individual animals (1 to 6340 L1/g). Overall mortality was 72% (range: 28% to 100%) at seven weeks PI. In conclusion, abdominal angiostrongylosis in M. musculus presents high mortality and a very variable and irregular elimination of L1 in feces.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000200026Angiostrongylus costaricensisabdominal angiostrongylosisMus musculuscoevolution |
| spellingShingle | Cibele Canali Aline H Goulart Carlos Graeff-Teixeira Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss Mice Memorias do Instituto Oswaldo Cruz Angiostrongylus costaricensis abdominal angiostrongylosis Mus musculus coevolution |
| title | Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss Mice |
| title_full | Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss Mice |
| title_fullStr | Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss Mice |
| title_full_unstemmed | Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss Mice |
| title_short | Study on the Elimination of Angiostrongylus costaricensis First Stage Larvae in the Experimental Infection of Swiss Mice |
| title_sort | study on the elimination of angiostrongylus costaricensis first stage larvae in the experimental infection of swiss mice |
| topic | Angiostrongylus costaricensis abdominal angiostrongylosis Mus musculus coevolution |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000200026 |
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