Targeting immune cell types of tumor microenvironment to overcome resistance to PD-1/PD-L1 blockade in lung cancer

Targeting immune cell types of tumor microenvironment to overcome resistance to PD-1/PD-L1 blockade in lung cancer

Lung cancer is the common malignant tumor with the highest mortality rate. Lung cancer patients have achieved benefits from immunotherapy, including immune checkpoint inhibitors (ICIs) therapy. Unfortunately, cancer patients acquire adaptive immune resistance, leading to poor prognosis. Tumor microe...

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Bibliographic Details
Main Authors: Man Wang, Lijie Zhu, Xiaoxu Yang, Jiahui Li, Yu’e Liu, Ying Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
TME
PD-L1
PD-1
time
immunotherapy
resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1132158/full

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