Oral Drug Delivery Systems Based on Ordered Mesoporous Silica Nanoparticles for Modulating the Release of Aprepitant

Oral Drug Delivery Systems Based on Ordered Mesoporous Silica Nanoparticles for Modulating the Release of Aprepitant

Two different types of ordered mesoporous nanoparticles, namely MCM-41 and MCM-48, with similar pore sizes but different pore connectivity, were loaded with aprepitant via a passive diffusion method. The percentage of the loaded active agent, along with the encapsulation efficiency, was evaluated us...

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Bibliographic Details
Main Authors: Theodora Christoforidou, Dimitra Giasafaki, Eleftherios G. Andriotis, Nikolaos Bouropoulos, Nikoleta F. Theodoroula, Ioannis S. Vizirianakis, Theodore Steriotis, Georgia Charalambopoulou, Dimitrios G. Fatouros
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
mesoporous materials
poorly soluble drugs
aprepitant
oral delivery
Online Access:https://www.mdpi.com/1422-0067/22/4/1896

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