Prognostic prediction using a gene signature developed based on exhausted T cells for liver cancer patients

Prognostic prediction using a gene signature developed based on exhausted T cells for liver cancer patients

Background: Liver hepatocellular carcinoma (LIHC) is a solid primary malignancy with poor prognosis. This study discovered key prognostic genes based on T cell exhaustion and used them to develop a prognostic prediction model for LIHC. Methods: SingleR's annotations combined with Seurat was use...

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Bibliographic Details
Main Authors: Yu Zhou, Wanrui Wu, Wei Cai, Dong Zhang, Weiwei Zhang, Yunling Luo, Fujing Cai, Zhenjing Shi
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Single cell profile
T cell exhaustion
Prognosis signature
Liver hepatocellular carcinoma (LIHC)
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024041872

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