Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
J Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at our disposal the new rapid-acting insulin analog...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2012-01-01
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| Series: | Diabetes, Metabolic Syndrome and Obesity |
| Online Access: | http://www.dovepress.com/cumulative-clinical-experience-with-use-of-insulin-lispro-critical-app-a9025 |
| _version_ | 1811174121774514176 |
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| author | Uy J Fogelfeld L Guerra Y |
| author_facet | Uy J Fogelfeld L Guerra Y |
| author_sort | Uy J |
| collection | DOAJ |
| description | J Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at our disposal the new rapid-acting insulin analogs, of which insulin lispro was the first to become commercially available. While the differences in pharmacokinetic and pharmacodynamic characteristics are indisputable, the clinical benefits attained by these changes have not been as clear. In the present review, we discuss the structure, pharmacology, and landmark studies related to insulin lispro. The clinical characteristics of insulin lispro are compared with those of insulin regular and other insulin analogs in different clinical situations. Also included are the aspects of quality of life and cost-effectiveness that may modify the modern practitioner's decision to adopt one type of insulin over another.Keywords: insulin lispro, rapid-acting, insulin, analog |
| first_indexed | 2024-04-10T17:58:05Z |
| format | Article |
| id | doaj.art-28a2a29c6aa54edda42f5cf654835b30 |
| institution | Directory Open Access Journal |
| issn | 1178-7007 |
| language | English |
| last_indexed | 2024-04-10T17:58:05Z |
| publishDate | 2012-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj.art-28a2a29c6aa54edda42f5cf654835b302023-02-02T16:52:22ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072012-01-012012default110Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerationsUy JFogelfeld LGuerra YJ Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at our disposal the new rapid-acting insulin analogs, of which insulin lispro was the first to become commercially available. While the differences in pharmacokinetic and pharmacodynamic characteristics are indisputable, the clinical benefits attained by these changes have not been as clear. In the present review, we discuss the structure, pharmacology, and landmark studies related to insulin lispro. The clinical characteristics of insulin lispro are compared with those of insulin regular and other insulin analogs in different clinical situations. Also included are the aspects of quality of life and cost-effectiveness that may modify the modern practitioner's decision to adopt one type of insulin over another.Keywords: insulin lispro, rapid-acting, insulin, analoghttp://www.dovepress.com/cumulative-clinical-experience-with-use-of-insulin-lispro-critical-app-a9025 |
| spellingShingle | Uy J Fogelfeld L Guerra Y Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations Diabetes, Metabolic Syndrome and Obesity |
| title | Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations |
| title_full | Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations |
| title_fullStr | Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations |
| title_full_unstemmed | Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations |
| title_short | Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations |
| title_sort | cumulative clinical experience with use of insulin lispro critical appraisal role in therapy and patient considerations |
| url | http://www.dovepress.com/cumulative-clinical-experience-with-use-of-insulin-lispro-critical-app-a9025 |
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