Short-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaire

Abstract Background Impaired quality of life (QOL) is common in coronary heart disease and is the major indications for coronary artery bypass graft (CABG) operations. This study aims to compare the QOL of patients with coronary heart disease before and after CABG surgery. Results A translated Arabi...

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Main Authors: Mohammad Abdallah, Shymaa Mamdouh, Abdel-Hady El-Gilany, Wael Abdel-Aziz, Olfat Farag, Noha ElAdawy
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:The Cardiothoracic Surgeon
Subjects:
Online Access:http://link.springer.com/article/10.1186/s43057-020-00028-x
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author Mohammad Abdallah
Shymaa Mamdouh
Abdel-Hady El-Gilany
Wael Abdel-Aziz
Olfat Farag
Noha ElAdawy
author_facet Mohammad Abdallah
Shymaa Mamdouh
Abdel-Hady El-Gilany
Wael Abdel-Aziz
Olfat Farag
Noha ElAdawy
author_sort Mohammad Abdallah
collection DOAJ
description Abstract Background Impaired quality of life (QOL) is common in coronary heart disease and is the major indications for coronary artery bypass graft (CABG) operations. This study aims to compare the QOL of patients with coronary heart disease before and after CABG surgery. Results A translated Arabic version of the Mac-New health-related QOL questionnaire was used to evaluate QOL improvement in 446 patients who benefited from elective CABG at Nasser Institute for Research and Treatment. There was a statistically significant improvement in physical, emotional, social, and global domains of QOL, as evaluated 3 and 6 months after surgery. Follow-up was 90.4% complete. At 3 months, multiple linear regression has shown that male patients (β = 0.48, p ≤ 0.001) and rural residence (β = 0.39, p ≤ 0.001) were significant independent predictors of improvement in physical QOL domain. While hypercholesterolemia (β = −0.20, −0.49, −0.37, −0.46, p ≤ 0.001), hypertension (β = −0.29, −0.39, p ≤ 0.001, β = −0.35, −β = 0.35, p = 0.001), and smoking (β = −0.79, p ≤ 0.001, β = −0.33, p = 0.04, β = −0.69, p ≤ 0.001, β = −0.47, p = 0.005) were significant predictors of worsening in physical, emotional, social, and global domains, respectively. At 6 months, low preoperative ejection fraction (EF) ≤ 40% was the strongest predictor of improvement (β = 0.54, 0.49, 0.44, and 0.52, p ≤ 0.001) in physical, emotional, social, and global domains of QOL, respectively. But, peripheral vascular disease (PVD) (β = −0.53, p = 0.05, β = −0.81, p = 0.005, β = −0.62, p = 0.03, β = −0.76, p = 0.008) and smoking (β = −0.53, p = 0.001, β = −0.42, p = 0.01, β = −0.42, p = 0.01, β = −0.41, p = 0.02) were significant predictors of worsening in physical, emotional, social, and global domains of QOL, respectively. Conclusions CABG surgery improved in all domains of QOL. Further studies are required to evaluate changes in QOL at longer period intervals.
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spelling doaj.art-28a3ed3102c243fa9d8259b09b9d2b9a2022-12-22T01:54:08ZengSpringerOpenThe Cardiothoracic Surgeon2662-22032020-09-012811710.1186/s43057-020-00028-xShort-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaireMohammad Abdallah0Shymaa Mamdouh1Abdel-Hady El-Gilany2Wael Abdel-Aziz3Olfat Farag4Noha ElAdawy5Department of Cardiothoracic Surgery, National Heart InstituteDepartment of Public Health and Preventive Medicine, Faculty of Medicine, Mansoura UniversityDepartment of Public Health and Preventive Medicine, Faculty of Medicine, Mansoura UniversityDepartment of Cardiothoracic Surgery, Faculty of Medicine, Mansoura UniversityDepartment of Public Health and Preventive Medicine, Faculty of Medicine, Mansoura UniversityDepartment of Public Health and Preventive Medicine, Faculty of Medicine, Mansoura UniversityAbstract Background Impaired quality of life (QOL) is common in coronary heart disease and is the major indications for coronary artery bypass graft (CABG) operations. This study aims to compare the QOL of patients with coronary heart disease before and after CABG surgery. Results A translated Arabic version of the Mac-New health-related QOL questionnaire was used to evaluate QOL improvement in 446 patients who benefited from elective CABG at Nasser Institute for Research and Treatment. There was a statistically significant improvement in physical, emotional, social, and global domains of QOL, as evaluated 3 and 6 months after surgery. Follow-up was 90.4% complete. At 3 months, multiple linear regression has shown that male patients (β = 0.48, p ≤ 0.001) and rural residence (β = 0.39, p ≤ 0.001) were significant independent predictors of improvement in physical QOL domain. While hypercholesterolemia (β = −0.20, −0.49, −0.37, −0.46, p ≤ 0.001), hypertension (β = −0.29, −0.39, p ≤ 0.001, β = −0.35, −β = 0.35, p = 0.001), and smoking (β = −0.79, p ≤ 0.001, β = −0.33, p = 0.04, β = −0.69, p ≤ 0.001, β = −0.47, p = 0.005) were significant predictors of worsening in physical, emotional, social, and global domains, respectively. At 6 months, low preoperative ejection fraction (EF) ≤ 40% was the strongest predictor of improvement (β = 0.54, 0.49, 0.44, and 0.52, p ≤ 0.001) in physical, emotional, social, and global domains of QOL, respectively. But, peripheral vascular disease (PVD) (β = −0.53, p = 0.05, β = −0.81, p = 0.005, β = −0.62, p = 0.03, β = −0.76, p = 0.008) and smoking (β = −0.53, p = 0.001, β = −0.42, p = 0.01, β = −0.42, p = 0.01, β = −0.41, p = 0.02) were significant predictors of worsening in physical, emotional, social, and global domains of QOL, respectively. Conclusions CABG surgery improved in all domains of QOL. Further studies are required to evaluate changes in QOL at longer period intervals.http://link.springer.com/article/10.1186/s43057-020-00028-xQuality of lifeCoronary artery diseaseCoronary artery bypass graft surgery
spellingShingle Mohammad Abdallah
Shymaa Mamdouh
Abdel-Hady El-Gilany
Wael Abdel-Aziz
Olfat Farag
Noha ElAdawy
Short-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaire
The Cardiothoracic Surgeon
Quality of life
Coronary artery disease
Coronary artery bypass graft surgery
title Short-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaire
title_full Short-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaire
title_fullStr Short-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaire
title_full_unstemmed Short-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaire
title_short Short-term outcomes of surgical myocardial revascularization on health-related quality of life: a validation of the Arabic MacNew heart disease questionnaire
title_sort short term outcomes of surgical myocardial revascularization on health related quality of life a validation of the arabic macnew heart disease questionnaire
topic Quality of life
Coronary artery disease
Coronary artery bypass graft surgery
url http://link.springer.com/article/10.1186/s43057-020-00028-x
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