Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal Outcome
The article describes the clinical observation of thrombosis of prosthetic cardiac valve in a 51-year-old female patient, 9 years after surgical intervention for a degenerative aortic valve disease with the installation of mechanical prosthesis into the aortal position and further warfarin medicatio...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2020-07-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/2226 |
| _version_ | 1797232073858088960 |
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| author | A. A. Novoselova S. S. Yakushin |
| author_facet | A. A. Novoselova S. S. Yakushin |
| author_sort | A. A. Novoselova |
| collection | DOAJ |
| description | The article describes the clinical observation of thrombosis of prosthetic cardiac valve in a 51-year-old female patient, 9 years after surgical intervention for a degenerative aortic valve disease with the installation of mechanical prosthesis into the aortal position and further warfarin medication, with absence of international normalized ratio (INR) control over the past six months. The patient's condition worsened under the “mask” of decompensation of left ventricular circulatory failure; pulmonary embolism and acute coronary syndrome were also excluded. At the same time, the negative dynamics of the cardiac ultrasound data were underestimated: the appearance of prosthetic dysfunction, an increase in the degree of valve regurgitation, severe pulmonary hypertension, as well as anamnestic data (double acute cerebrovascular accident and lack of INR control for a long time, lability of its values during index hospitalization).This case can be important in terms of clarifying the reasons for the decompensation of chronic cardiac failure in patients with valvular defects and mechanical valve prosthetics, especially in cases of irregular INR monitoring or not being it in the target range, and progressive negative dynamics of the cardiac ultrasound data. |
| first_indexed | 2024-03-08T14:00:50Z |
| format | Article |
| id | doaj.art-28a7ab64560d4749b23db7d18beb19a4 |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:54:29Z |
| publishDate | 2020-07-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-28a7ab64560d4749b23db7d18beb19a42024-04-01T07:43:39ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532020-07-0116339940310.20996/1819-6446-2020-06-131755Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal OutcomeA. A. Novoselova0S. S. Yakushin1Ryazan State Medical University named after Academician I.P. PavlovRyazan State Medical University named after Academician I.P. PavlovThe article describes the clinical observation of thrombosis of prosthetic cardiac valve in a 51-year-old female patient, 9 years after surgical intervention for a degenerative aortic valve disease with the installation of mechanical prosthesis into the aortal position and further warfarin medication, with absence of international normalized ratio (INR) control over the past six months. The patient's condition worsened under the “mask” of decompensation of left ventricular circulatory failure; pulmonary embolism and acute coronary syndrome were also excluded. At the same time, the negative dynamics of the cardiac ultrasound data were underestimated: the appearance of prosthetic dysfunction, an increase in the degree of valve regurgitation, severe pulmonary hypertension, as well as anamnestic data (double acute cerebrovascular accident and lack of INR control for a long time, lability of its values during index hospitalization).This case can be important in terms of clarifying the reasons for the decompensation of chronic cardiac failure in patients with valvular defects and mechanical valve prosthetics, especially in cases of irregular INR monitoring or not being it in the target range, and progressive negative dynamics of the cardiac ultrasound data.https://www.rpcardio.online/jour/article/view/2226stenosis of aortic valvemechanical prosthesisvalve thrombosiswarfarin |
| spellingShingle | A. A. Novoselova S. S. Yakushin Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal Outcome Рациональная фармакотерапия в кардиологии stenosis of aortic valve mechanical prosthesis valve thrombosis warfarin |
| title | Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal Outcome |
| title_full | Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal Outcome |
| title_fullStr | Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal Outcome |
| title_full_unstemmed | Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal Outcome |
| title_short | Thrombosis of Prosthetic Cardiac Valve: Difficulties of Diagnostics on the Example of a Clinical Case with Lethal Outcome |
| title_sort | thrombosis of prosthetic cardiac valve difficulties of diagnostics on the example of a clinical case with lethal outcome |
| topic | stenosis of aortic valve mechanical prosthesis valve thrombosis warfarin |
| url | https://www.rpcardio.online/jour/article/view/2226 |
| work_keys_str_mv | AT aanovoselova thrombosisofprostheticcardiacvalvedifficultiesofdiagnosticsontheexampleofaclinicalcasewithlethaloutcome AT ssyakushin thrombosisofprostheticcardiacvalvedifficultiesofdiagnosticsontheexampleofaclinicalcasewithlethaloutcome |