Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort study

BackgroundPatients with serious mental disorders have poorer healthcare outcomes at the end of life and are at greater risk of dying from unnatural causes.AimsTo explore place of death and demographic and clinical correlates of unnatural causes of death in patients with serious mental disorders.Meth...

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Main Authors: Rebecca Wilson, Fiona Gaughran, Tara Whitburn, Irene J. Higginson, Wei Gao
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:BJPsych Open
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S205647241900005X/type/journal_article
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author Rebecca Wilson
Fiona Gaughran
Tara Whitburn
Irene J. Higginson
Wei Gao
author_facet Rebecca Wilson
Fiona Gaughran
Tara Whitburn
Irene J. Higginson
Wei Gao
author_sort Rebecca Wilson
collection DOAJ
description BackgroundPatients with serious mental disorders have poorer healthcare outcomes at the end of life and are at greater risk of dying from unnatural causes.AimsTo explore place of death and demographic and clinical correlates of unnatural causes of death in patients with serious mental disorders.MethodRoutinely collected patient data were used to explore bivariate and adjusted associations between covariates and natural/unnatural cause of death.ResultsIn multivariable analysis (n = 1029), dying at home (odds ratio (OR) = 1.87, 95% CI 1.03–3.40), ‘other’ locations (OR = 16.50, 95% CI 7.57–36.00), younger age (OR = 17.26, 95% CI 8.28–36.00) and a diagnosis other than schizophrenia spectrum disorder (OR = 1.69, 95% CI 1.04–2.73) were correlates of unnatural cause of death.ConclusionsDeaths from unnatural causes were high and more likely to occur at home and non-healthcare settings. Unnatural causes of death were higher in younger patients with non-schizophrenia spectrum disorder diagnoses.Declaration of interestF.G. has received support or honoraria for CME, advisory work and lectures from Bristol-Myers Squibb, Janssen, Lundbeck, Otsuka, Roche, and Sunovion, and has a family member with professional links to Lilly and GSK, including shares.
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spelling doaj.art-28a83d59ec45448e91ae59d241a9e9e72023-03-09T12:28:48ZengCambridge University PressBJPsych Open2056-47242019-03-01510.1192/bjo.2019.5Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort studyRebecca Wilson0https://orcid.org/0000-0003-4709-7260Fiona Gaughran1Tara Whitburn2Irene J. Higginson3Wei Gao4Research Associate, Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, UKLead Consultant/Senior Lecturer, Psychosis Studies Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London; and National Psychosis Unit, South London and Maudsley NHS Foundation Trust, UKConsultant in Palliative Medicine, Barts Health NHS Trust, Macmillan Palliative Care Team, St Bartholomew's Hospital, UKHead of Department, Head of Division and Director of Cicely Saunders Institute, Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, UKReader in Statistics and Epidemiology, Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, UKBackgroundPatients with serious mental disorders have poorer healthcare outcomes at the end of life and are at greater risk of dying from unnatural causes.AimsTo explore place of death and demographic and clinical correlates of unnatural causes of death in patients with serious mental disorders.MethodRoutinely collected patient data were used to explore bivariate and adjusted associations between covariates and natural/unnatural cause of death.ResultsIn multivariable analysis (n = 1029), dying at home (odds ratio (OR) = 1.87, 95% CI 1.03–3.40), ‘other’ locations (OR = 16.50, 95% CI 7.57–36.00), younger age (OR = 17.26, 95% CI 8.28–36.00) and a diagnosis other than schizophrenia spectrum disorder (OR = 1.69, 95% CI 1.04–2.73) were correlates of unnatural cause of death.ConclusionsDeaths from unnatural causes were high and more likely to occur at home and non-healthcare settings. Unnatural causes of death were higher in younger patients with non-schizophrenia spectrum disorder diagnoses.Declaration of interestF.G. has received support or honoraria for CME, advisory work and lectures from Bristol-Myers Squibb, Janssen, Lundbeck, Otsuka, Roche, and Sunovion, and has a family member with professional links to Lilly and GSK, including shares.https://www.cambridge.org/core/product/identifier/S205647241900005X/type/journal_articleSerious mental disorderunnatural cause of deathplace of deathroutine datamortality
spellingShingle Rebecca Wilson
Fiona Gaughran
Tara Whitburn
Irene J. Higginson
Wei Gao
Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort study
BJPsych Open
Serious mental disorder
unnatural cause of death
place of death
routine data
mortality
title Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort study
title_full Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort study
title_fullStr Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort study
title_full_unstemmed Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort study
title_short Place of death and other factors associated with unnatural mortality in patients with serious mental disorders: population-based retrospective cohort study
title_sort place of death and other factors associated with unnatural mortality in patients with serious mental disorders population based retrospective cohort study
topic Serious mental disorder
unnatural cause of death
place of death
routine data
mortality
url https://www.cambridge.org/core/product/identifier/S205647241900005X/type/journal_article
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