Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages

Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages

The G protein-coupled receptor 37 (GPR37) has been reported to be expressed in macrophages and the activation of GPR37 by its ligand/agonist, and it can regulate macrophage-associated functions and inflammatory responses. Since our previous work identified that osteocalcin (OCN) acts as an endogenou...

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Bibliographic Details
Main Authors: Zhengjiang Qian, Chunhua Liu, Hongchao Li, Haiyang Yang, Jianhao Wu, Jing Liu, Yanjiao Li, Xuhui Chen, Jianyang Xu, Xiang Li
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomedicines
Subjects:
osteocalcin
GPR37
macrophage
lipopolysaccharide
acute inflammation
Online Access:https://www.mdpi.com/2227-9059/10/5/1006

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