Utility of Whole Genome Sequencing for Population Screening of Deafness-Related Genetic Variants and Cytomegalovirus Infection in Newborns

Utility of Whole Genome Sequencing for Population Screening of Deafness-Related Genetic Variants and Cytomegalovirus Infection in Newborns

Background: Hearing loss affects approximately two out of every 1,000 newborns. Genetic factors and congenital cytomegalovirus (CMV) infections account for around 90% of the etiology. The purpose of this study was to develop and test a whole genome sequencing (WGS) approach to detect deafness-relate...

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Bibliographic Details
Main Authors: Jiale Xiang, Hongfu Zhang, Xiangzhong Sun, Junqing Zhang, Zhenpeng Xu, Jun Sun, Zhiyu Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
WGS
hearing loss
newborns
genetic variation
cytomegalovirus infection
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.883617/full

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