Quantifying shifts in natural selection on codon usage between protein regions: a population genetics approach

Abstract Background Codon usage bias (CUB), the non-uniform usage of synonymous codons, occurs across all domains of life. Adaptive CUB is hypothesized to result from various selective pressures, including selection for efficient ribosome elongation, accurate translation, mRNA secondary structure, a...

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Bibliographic Details
Main Authors: Alexander L. Cope, Michael A. Gilchrist
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-022-08635-0