TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.

TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.

Transmembrane Protein 41B (TMEM41B) and Vacuole Membrane Protein 1 (VMP1) are two ER-associated lipid scramblases that play a role in autophagosome formation and cellular lipid metabolism. TMEM41B is also a recently validated host factor required by flaviviruses and coronaviruses. However, the exact...

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Bibliographic Details
Main Authors: Meisam Yousefi, Wai Suet Lee, Biaoguo Yan, Liang Cui, Cythia Lingli Yong, Xin Yap, Kwan Sing Leona Tay, Wenjie Qiao, Dewei Tan, Nur Insyirah Nurazmi, Martin Linster, Gavin J D Smith, Yie Hou Lee, Jan E Carette, Eng Eong Ooi, Kuan Rong Chan, Yaw Shin Ooi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010763

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