Characterization of Endocannabinoid-Metabolizing Enzymes in Human Peripheral Blood Mononuclear Cells under Inflammatory Conditions

Characterization of Endocannabinoid-Metabolizing Enzymes in Human Peripheral Blood Mononuclear Cells under Inflammatory Conditions

Endocannabinoid-metabolizing enzymes are downregulated in response to lipopolysaccharide (LPS)-induced inflammation in mice, which may serve as a negative feedback mechanism to increase endocannabinoid levels and reduce inflammation. Increased plasma levels of the pro-inflammatory cytokine interleuk...

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Bibliographic Details
Main Authors: Brittany N. Szafran, Jung Hwa Lee, Abdolsamad Borazjani, Peter Morrison, Grace Zimmerman, Kelly L. Andrzejewski, Matthew K. Ross, Barbara L.F. Kaplan
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
endocannabinoids
MAGL
CES
Huntington’s disease
Online Access:https://www.mdpi.com/1420-3049/23/12/3167

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