Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats

Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats

Objective(s): We aimed to investigate the gastroprotective effect of lactoferrin (LF; 100 & 300 mg/kg) in male Wistar rats versus gastric ulcers induced by 96% ethanol.Materials and Methods: Rats were randomly allocated into 4 groups: control, ethanol, ethanol+LF100, and ethanol+LF300. LF100 &am...

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Bibliographic Details
Main Authors: Gihan Asaad, Rasha Mostafa
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-12-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
anti-oxidant
anti-inflammatory
ethanol
gastric ulcer
lactoferrin
Online Access:https://ijbms.mums.ac.ir/article_21185_bf7b026b4a0f5f9092c8e074bcb0a07c.pdf

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