Allostery Modulates Interactions between Proteasome Core Particles and Regulatory Particles

Allostery—regulation at distant sites is a key concept in biology. The proteasome exhibits multiple forms of allosteric regulation. This regulatory communication can span a distance exceeding 100 Ångstroms and can modulate interactions between the two major proteasome modules: its core particle and...

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Bibliographic Details
Main Authors: Philip Coffino, Yifan Cheng
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/6/764

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