Novel Cocrystals of Vonoprazan: Machine Learning-Assisted Discovery

Novel Cocrystals of Vonoprazan: Machine Learning-Assisted Discovery

Vonoprazan (VPZ) is the first-in-class potassium-competitive acid blocker (P-CAB), and has many advantages over proton pump inhibitors (PPIs). It is administered as a fumarate salt for the treatment of acid-related diseases, including reflux esophagitis, gastric ulcer, and duodenal ulcer, and for er...

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Bibliographic Details
Main Authors: Min-Jeong Lee, Ji-Yoon Kim, Paul Kim, In-Seo Lee, Medard E. Mswahili, Young-Seob Jeong, Guang J. Choi
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
pharmaceutical cocrystal
vonoprazan
P-CAB
machine learning
stability
Online Access:https://www.mdpi.com/1999-4923/14/2/429

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