Analysis of drug resistance in HIV protease

Analysis of drug resistance in HIV protease

Abstract Background Drug resistance in HIV is the major problem limiting effective antiviral therapy. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques can also be used to select protease mutants for...

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Bibliographic Details
Main Authors: Shrikant D. Pawar, Christopher Freas, Irene T. Weber, Robert W. Harrison
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Bioinformatics
Subjects:
HIV protease
Drug resistance
Machine learning
RBM
Structure-based
Online Access:http://link.springer.com/article/10.1186/s12859-018-2331-y

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