Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-Study

Background: Evidence has shown that poor adherence to vascular medications contributes to a considerable proportion of all cardiovascular disease (CVD) events and mortality. The aim of the present work was to examine patients’ beliefs/views that affect their level of adherence to the assigned medica...

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Main Authors: Vasiliki Belitsi, Thomas Tsiampalis, Matina Kouvari, Vasiliki Kalantzi, Odysseas Androutsos, Fotini Bonoti, Demosthenes B. Panagiotakos, Rena I. Kosti
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/9/1880
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author Vasiliki Belitsi
Thomas Tsiampalis
Matina Kouvari
Vasiliki Kalantzi
Odysseas Androutsos
Fotini Bonoti
Demosthenes B. Panagiotakos
Rena I. Kosti
author_facet Vasiliki Belitsi
Thomas Tsiampalis
Matina Kouvari
Vasiliki Kalantzi
Odysseas Androutsos
Fotini Bonoti
Demosthenes B. Panagiotakos
Rena I. Kosti
author_sort Vasiliki Belitsi
collection DOAJ
description Background: Evidence has shown that poor adherence to vascular medications contributes to a considerable proportion of all cardiovascular disease (CVD) events and mortality. The aim of the present work was to examine patients’ beliefs/views that affect their level of adherence to the assigned medical treatment in the context of a multi-center study in Greece. Methods: Between July 2022 and April 2023, 1988 patients (1180 females) with established cardiovascular disease or relevant cardiometabolic disorders were chosen from seven medical centers in Greece. The 4-item Morisky Medication Adherence Questionnaire gauged medication adherence and investigated patients’ beliefs/views regarding treatment. Results: Among participants, 51.2% showed perfect medication adherence, contrasting with 48.8% displaying poor adherence. Patients with negative medication beliefs were around three times more likely to be non-adherent (OR = 2.73; 95% CI = 2.28–3.28). Non-adherers held concerns about drug efficacy (OR = 2.34; 95% CI = 1.10–4.97) and favored alternative therapies (OR = 2.25; 95% CI = 1.75–2.91). Conclusion: The findings highlight the significance of addressing patient beliefs/views to improve medication adherence. The distinct Mediterranean context, influenced by cultural, socioeconomic, and clinical factors, emphasizes the need for tailored interventions. This underscores the call for contextually sensitive strategies to boost medication adherence and improve health outcomes in this unique region.
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spelling doaj.art-28d339a9b33a4c4bb0fc2824c5b5db362023-11-19T11:37:35ZengMDPI AGLife2075-17292023-09-01139188010.3390/life13091880Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-StudyVasiliki Belitsi0Thomas Tsiampalis1Matina Kouvari2Vasiliki Kalantzi3Odysseas Androutsos4Fotini Bonoti5Demosthenes B. Panagiotakos6Rena I. Kosti7Department of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, GreeceDepartment of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, GreeceDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17676 Athens, GreeceDepartment of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, GreeceDepartment of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, GreeceDepartment of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, GreeceDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17676 Athens, GreeceDepartment of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, GreeceBackground: Evidence has shown that poor adherence to vascular medications contributes to a considerable proportion of all cardiovascular disease (CVD) events and mortality. The aim of the present work was to examine patients’ beliefs/views that affect their level of adherence to the assigned medical treatment in the context of a multi-center study in Greece. Methods: Between July 2022 and April 2023, 1988 patients (1180 females) with established cardiovascular disease or relevant cardiometabolic disorders were chosen from seven medical centers in Greece. The 4-item Morisky Medication Adherence Questionnaire gauged medication adherence and investigated patients’ beliefs/views regarding treatment. Results: Among participants, 51.2% showed perfect medication adherence, contrasting with 48.8% displaying poor adherence. Patients with negative medication beliefs were around three times more likely to be non-adherent (OR = 2.73; 95% CI = 2.28–3.28). Non-adherers held concerns about drug efficacy (OR = 2.34; 95% CI = 1.10–4.97) and favored alternative therapies (OR = 2.25; 95% CI = 1.75–2.91). Conclusion: The findings highlight the significance of addressing patient beliefs/views to improve medication adherence. The distinct Mediterranean context, influenced by cultural, socioeconomic, and clinical factors, emphasizes the need for tailored interventions. This underscores the call for contextually sensitive strategies to boost medication adherence and improve health outcomes in this unique region.https://www.mdpi.com/2075-1729/13/9/1880medication adherenceheart diseasecardiometabolic disordersbeliefsviewstreatment
spellingShingle Vasiliki Belitsi
Thomas Tsiampalis
Matina Kouvari
Vasiliki Kalantzi
Odysseas Androutsos
Fotini Bonoti
Demosthenes B. Panagiotakos
Rena I. Kosti
Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-Study
Life
medication adherence
heart disease
cardiometabolic disorders
beliefs
views
treatment
title Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-Study
title_full Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-Study
title_fullStr Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-Study
title_full_unstemmed Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-Study
title_short Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients with Cardiovascular Diseases and Cardiometabolic Disorders in Greece—The IACT-Study
title_sort exploring patient beliefs and medication adherence in the mediterranean context a cross sectional study in patients with cardiovascular diseases and cardiometabolic disorders in greece the iact study
topic medication adherence
heart disease
cardiometabolic disorders
beliefs
views
treatment
url https://www.mdpi.com/2075-1729/13/9/1880
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