Influence of High Pass Filter Settings on Motor Evoked Potentials
ObjectiveMotor evoked potentials (MEP), obtained by transcranial magnetic stimulation (TMS) are a common tool in clinical research and diagnostic. Nevertheless, reports regarding the influence of filter settings on MEP are sparse. Here, we compared MEP amplitudes and signal to noise ratio (SNR) usin...
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Frontiers Media S.A.
2021-04-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2021.665258/full |
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| author | Petyo Nikolov Petyo Nikolov Shady S. Hassan Shady S. Hassan Alfons Schnitzler Alfons Schnitzler Stefan J. Groiss Stefan J. Groiss |
| author_facet | Petyo Nikolov Petyo Nikolov Shady S. Hassan Shady S. Hassan Alfons Schnitzler Alfons Schnitzler Stefan J. Groiss Stefan J. Groiss |
| author_sort | Petyo Nikolov |
| collection | DOAJ |
| description | ObjectiveMotor evoked potentials (MEP), obtained by transcranial magnetic stimulation (TMS) are a common tool in clinical research and diagnostic. Nevertheless, reports regarding the influence of filter settings on MEP are sparse. Here, we compared MEP amplitudes and signal to noise ratio (SNR) using multiple high pass filter (HPF) and notch filter settings.Materials and MethodsTwenty healthy subjects were enrolled in the study. Recruitment curves were obtained with HPF settings varied at 10, 20, 50, and 100 Hz. The four HPF settings were tested both with and without 50 Hz active notch filter. Low pass filter was kept constant at 5 kHz.ResultsMEP amplitudes with HPF at 10 and 20 Hz were significantly higher than at 100 Hz, regardless of the notch filter. However, SNR did not differ among HPF settings. An active notch filter significantly improved SNR.ConclusionThe reduction in MEP amplitudes with HPF above 20 Hz may be due to noise reduction, since the different HPF conditions did not alter SNR. Thus, higher HPF above 50 Hz may be an option to reduce noise, the use of a notch filter may even improve SNR.SignificanceOur findings are relevant for the selection of filter settings and might be of importance to any researcher who utilizes TMS-MEP. |
| first_indexed | 2024-12-17T22:24:10Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-17T22:24:10Z |
| publishDate | 2021-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-28d37d90e654448788d37c23851c73352022-12-21T21:30:24ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2021-04-011510.3389/fnins.2021.665258665258Influence of High Pass Filter Settings on Motor Evoked PotentialsPetyo Nikolov0Petyo Nikolov1Shady S. Hassan2Shady S. Hassan3Alfons Schnitzler4Alfons Schnitzler5Stefan J. Groiss6Stefan J. Groiss7Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Neurology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyInstitute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Neurology, Medical Faculty, Assiut University Hospital, Assiut, EgyptInstitute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Neurology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyInstitute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Neurology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyObjectiveMotor evoked potentials (MEP), obtained by transcranial magnetic stimulation (TMS) are a common tool in clinical research and diagnostic. Nevertheless, reports regarding the influence of filter settings on MEP are sparse. Here, we compared MEP amplitudes and signal to noise ratio (SNR) using multiple high pass filter (HPF) and notch filter settings.Materials and MethodsTwenty healthy subjects were enrolled in the study. Recruitment curves were obtained with HPF settings varied at 10, 20, 50, and 100 Hz. The four HPF settings were tested both with and without 50 Hz active notch filter. Low pass filter was kept constant at 5 kHz.ResultsMEP amplitudes with HPF at 10 and 20 Hz were significantly higher than at 100 Hz, regardless of the notch filter. However, SNR did not differ among HPF settings. An active notch filter significantly improved SNR.ConclusionThe reduction in MEP amplitudes with HPF above 20 Hz may be due to noise reduction, since the different HPF conditions did not alter SNR. Thus, higher HPF above 50 Hz may be an option to reduce noise, the use of a notch filter may even improve SNR.SignificanceOur findings are relevant for the selection of filter settings and might be of importance to any researcher who utilizes TMS-MEP.https://www.frontiersin.org/articles/10.3389/fnins.2021.665258/fulltranscramial magnetic stimulationmotor evoked potentialhigh pass filternotch filterartifacts |
| spellingShingle | Petyo Nikolov Petyo Nikolov Shady S. Hassan Shady S. Hassan Alfons Schnitzler Alfons Schnitzler Stefan J. Groiss Stefan J. Groiss Influence of High Pass Filter Settings on Motor Evoked Potentials Frontiers in Neuroscience transcramial magnetic stimulation motor evoked potential high pass filter notch filter artifacts |
| title | Influence of High Pass Filter Settings on Motor Evoked Potentials |
| title_full | Influence of High Pass Filter Settings on Motor Evoked Potentials |
| title_fullStr | Influence of High Pass Filter Settings on Motor Evoked Potentials |
| title_full_unstemmed | Influence of High Pass Filter Settings on Motor Evoked Potentials |
| title_short | Influence of High Pass Filter Settings on Motor Evoked Potentials |
| title_sort | influence of high pass filter settings on motor evoked potentials |
| topic | transcramial magnetic stimulation motor evoked potential high pass filter notch filter artifacts |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2021.665258/full |
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