Formulation and Characterization of Carbopol-934 Based Kojic Acid-Loaded Smart Nanocrystals: A Solubility Enhancement Approach

Formulation and Characterization of Carbopol-934 Based Kojic Acid-Loaded Smart Nanocrystals: A Solubility Enhancement Approach

Kojic acid (KA) is a BCS class II drug having low solubility and high permeability. This study was designed to enhance the aqueous solubility of KA, as well as its dissolution rate and, in turn, bioavailability, by formulating its smart nanocrystals. Nanocrystals of pure KA were formulated by the to...

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Bibliographic Details
Main Authors: Barkat Ali Khan, Maryam Waheed, Khaled M. Hosny, Waleed Y. Rizg, Samar S. Murshid, Majed Alharbi, Muhammad Khalid Khan
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Polymers
Subjects:
sustainability of natural resources
nanocrystals
kojic acid
solubility enhancement
top-down technique
Online Access:https://www.mdpi.com/2073-4360/14/7/1489

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