Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane
IntroductionThis study aimed to examine the foveal stereo deviations in the different ectopic inner foveal layer (EIFL) stages of idiopathic epiretinal membrane (iERM) and assess its predictive utility for the baseline and postoperative best-corrected visual acuity (BCVA).MethodsBased on the calcula...
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1109471/full |
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| author | Zhengxi Zhang Jianbo Mao Jianbo Mao Jimeng Lao Nuo Chen Xinyi Deng Yijing Chen Jiwei Tao Yiqi Chen Yiqi Chen Lijun Shen |
| author_facet | Zhengxi Zhang Jianbo Mao Jianbo Mao Jimeng Lao Nuo Chen Xinyi Deng Yijing Chen Jiwei Tao Yiqi Chen Yiqi Chen Lijun Shen |
| author_sort | Zhengxi Zhang |
| collection | DOAJ |
| description | IntroductionThis study aimed to examine the foveal stereo deviations in the different ectopic inner foveal layer (EIFL) stages of idiopathic epiretinal membrane (iERM) and assess its predictive utility for the baseline and postoperative best-corrected visual acuity (BCVA).MethodsBased on the calculational combination of foveal displacements in the horizontal and vertical axial optical coherence tomography (OCT) images, the foveal stereotaxic displacement was estimated through the total distance (TD, the distance from the foveal bottom to the inner edge of displaced central foveal) and horizontal distance (HD, projection of the TD in the retinal plane). The preoperative TD, HD, and other OCT- and OCT angiography (OCTA)-related indicators were obtained. The correlations between structural parameters and baseline and postoperative BCVA were evaluated through correlation and multiple linear regression analyses.ResultsIn patients with advanced EIFL stage, there was a significant increase in the HD, TD, baseline log of the minimum angle of resolution unit for BCVA, central macular thickness (CMT), acircularity index, and incidence of microcystic macular edema (MME; p < 0.05). Further, they showed a decreased foveal avascular zone (FAZ) area and perimeter (p < 0.001). HD, TD, CMT, MME, FAZ area, and FAZ perimeter were significantly correlated with the baseline and postoperative BCVA (p < 0.05). TD had the highest correlation indexic and was an individual predictor of the baseline and postoperative BCVA. Moreover, FD-300 and MME were individual predictors of postoperative BCVA.DiscussionStereoscopic foveal deviations significantly correlated with the baseline and postoperative visual acuity. TD may be used as an independent prognostic factor for BCVA. |
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| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-09T21:27:47Z |
| publishDate | 2023-03-01 |
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| series | Frontiers in Medicine |
| spelling | doaj.art-28d5c1d0a2c64926bf88601bab54d4472023-03-27T12:38:12ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-03-011010.3389/fmed.2023.11094711109471Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membraneZhengxi Zhang0Jianbo Mao1Jianbo Mao2Jimeng Lao3Nuo Chen4Xinyi Deng5Yijing Chen6Jiwei Tao7Yiqi Chen8Yiqi Chen9Lijun Shen10School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaDepartment of Retina Center, Zhejiang Provincial People’s Hospital, Hangzhou, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, ChinaDepartment of Retina Center, Zhejiang Provincial People’s Hospital, Hangzhou, ChinaDepartment of Retina Center, Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, ChinaIntroductionThis study aimed to examine the foveal stereo deviations in the different ectopic inner foveal layer (EIFL) stages of idiopathic epiretinal membrane (iERM) and assess its predictive utility for the baseline and postoperative best-corrected visual acuity (BCVA).MethodsBased on the calculational combination of foveal displacements in the horizontal and vertical axial optical coherence tomography (OCT) images, the foveal stereotaxic displacement was estimated through the total distance (TD, the distance from the foveal bottom to the inner edge of displaced central foveal) and horizontal distance (HD, projection of the TD in the retinal plane). The preoperative TD, HD, and other OCT- and OCT angiography (OCTA)-related indicators were obtained. The correlations between structural parameters and baseline and postoperative BCVA were evaluated through correlation and multiple linear regression analyses.ResultsIn patients with advanced EIFL stage, there was a significant increase in the HD, TD, baseline log of the minimum angle of resolution unit for BCVA, central macular thickness (CMT), acircularity index, and incidence of microcystic macular edema (MME; p < 0.05). Further, they showed a decreased foveal avascular zone (FAZ) area and perimeter (p < 0.001). HD, TD, CMT, MME, FAZ area, and FAZ perimeter were significantly correlated with the baseline and postoperative BCVA (p < 0.05). TD had the highest correlation indexic and was an individual predictor of the baseline and postoperative BCVA. Moreover, FD-300 and MME were individual predictors of postoperative BCVA.DiscussionStereoscopic foveal deviations significantly correlated with the baseline and postoperative visual acuity. TD may be used as an independent prognostic factor for BCVA.https://www.frontiersin.org/articles/10.3389/fmed.2023.1109471/fullidiopathic epiretinal membraneretinaoptical coherence tomographyoptical coherence tomography angiographyepiretinal membrane |
| spellingShingle | Zhengxi Zhang Jianbo Mao Jianbo Mao Jimeng Lao Nuo Chen Xinyi Deng Yijing Chen Jiwei Tao Yiqi Chen Yiqi Chen Lijun Shen Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane Frontiers in Medicine idiopathic epiretinal membrane retina optical coherence tomography optical coherence tomography angiography epiretinal membrane |
| title | Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane |
| title_full | Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane |
| title_fullStr | Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane |
| title_full_unstemmed | Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane |
| title_short | Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane |
| title_sort | total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane |
| topic | idiopathic epiretinal membrane retina optical coherence tomography optical coherence tomography angiography epiretinal membrane |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1109471/full |
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